Examining retinal blood flow using a fast, line scanning adaptive optics scanning laser ophthalmoscope

Event Date

Imaging the human retinal blood flow at the level of an individual capillary requires the use of adaptive optics (AO) to overcome the ocular aberrations. Furthermore, to capture the temporal dynamics high speed imaging is required. We have developed a high speed (500 frames per second) multi-line partially confocal scanning laser ophthalmoscope (LpSLO) that uses a digital micromirror device (DMD). The DMD allows projection of multiple confocal lines at any direction and spacing, couple with the use of a high speed two dimensional CMOS camera allows simultaneous acquisition of the confocal and multiply scattered images. Here, we present blood vessel imaging results including flow velocities and also examine the vasodilation induced through the use of an external light stimulus.

Presenter

Nathan P. Doble
The Ohio State Univ. (United States)
Dr. Nathan Doble is a Professor in the College of Optometry and also in the Department of Ophthalmology and Visual Science at Ohio State University (OSU). Dr. Doble’s primary research interest is the development of high resolution optical imaging systems for the visualization of the human retina. Dr. Doble holds M.Sci, M.Sc. and Ph.D. degrees in the fields of laser physics and adaptive optics and performed postdoctoral work at the University of Rochester, NY, USA.