2026 Publications
Journal Papers & Peer Reviewed Proceedings
- Adams AC, Alfonso Garcia A, Noble Anbunesan S, Kraft L, Bec J, Lee HS, et al. Fluorescence lifetime imaging of 5-ALA-induced PpIX and autofluorescence for detecting infiltrating glioblastoma margins in patients. Biomed Opt Express. 2026 Mar 1;17(3):1267–78. doi:10.1364/BOE.581578 PubMed PMID: 41970566. PMCID: PMC13064626
- Ahamed A, Myat H, Rawat A, McPhillips LN, Islam MS. AI-augmented photon-trapping spectrometer-on-a-chip on silicon platform with extended near-infrared sensitivity. Advanced Photonics. 2026 Jan 19;8(01). doi:10.1117/1.AP.8.1.016008
- Bec J, Zhou X, Tipirneni Y, Chen S, Qi J, Iczkowski KA, et al. Label-free fluorescence lifetime imaging for rapid discrimination of high-grade prostate cancer in fresh biopsy cores: a feasibility study. J Biomed Opt. 2026 Mar 2;31(3):036001. doi:10.1117/1.JBO.31.3.036001 PubMed PMID: 41778026. PMCID: PMC12950611
- Goldschmidt S, Marcu L, Ehrlich K, Hassan MA, Rivas I, Birkeland A, et al. Label-free fluorescence lifetime imaging can distinguish cancer from healthy tissue in spontaneously occurring canine oral tumors. Sci Rep. 2026 Jan 23;16(1):6077. doi:10.1038/s41598-026-37001-3 PubMed PMID: 41578004. PMCID: PMC12902045
- Liu X, Adams AC, Zhou X, Bec J, Marcu L. Fluorescence properties of collagen types I-V: a comprehensive study of spectral and lifetime characteristics. J Biomed Opt. 2026 Jun;31(6):065001. doi: 10.1117/1.JBO.31.6.065001. Epub 2026 Jun 27. PMID: 42367579; PMCID: PMC13309843.
- Kasap B, Saffarpour M, Qian W, Joarder RR, Vali K, Ghiasi S. FOSTER: A Comprehensive Pipeline for Transabdominal Fetal Pulse Oximetry Validated in a Large Animal Model of Pregnancy. IEEE Trans Biomed Eng. 2026 Jun; 73(6):2155–64. doi:10.1109/TBME.2025.3623609. PubMed PMID: 41124068; PMCID: PMC13110799.
- Fowler R, Kasap B, Qian W, Joarder R, Vali K, Mani S, et al. Fetal pHocus: A Novel Approach to Non-Invasive Fetal Arterial Blood pH Assessment via Near-Infrared Spectroscopy. ACM Trans Comput Healthc. 2026 Apr; 7(2). doi:10.1145/3785412. PubMed PMID: 41852356; PMCID: PMC12994387.
- Lihe T, Kasap B, Vali K, Ghiasi S. HDFusion: Hierarchical Data Fusion for Robust Fetal Heart Rate Estimation using Transabdominal PPG Signals. ACM Trans Comput Healthc. 2026 Apr; 7(2):13. doi:10.1145/3785410. PubMed PMID: 41923781; PMCID: PMC13038302.
- Aparanji S, Zhao M, Nadig AS, Estrada HG, Hamilton D, Srinivasan VJ. Highly parallel, 1060 nm interferometric diffusing wave spectroscopy with a time-of-flight filter. Biomed Opt Express. 2026 Feb 10;17(3):1241–54. doi:10.1364/BOE.576865. PubMed PMID: 41970567; PMCID: PMC13064615.
- Parot VJ, Zhang Q, Baker WB, Robinson M, Srinivasan VJ. Optics and the Brain: introduction to the feature issue. Biomed Opt Express. 2026 May 1;17(5):2223–4. doi:10.1364/BOE.600351. PubMed PMID: 42145689; PMCID: PMC13178614.
- Zhang Y, Işıl Ç, Yang X, Li Y, Elia A, Atlan K, et al. Deep Learning-Enabled Virtual Multiplexed Immunostaining of Label-Free Tissue for Vascular Invasion Assessment. BME Front. 2026;7:0226. doi:10.34133/bmef.0226. PubMed PMID: 41676162; PMCID: PMC12886716.
- Costa PC, Kashani PG, Liu X, Chen A, Portes A, Bec J, et al. Pixel super-resolved fluorescence lifetime imaging using deep neural networks. Photonix. 2026;7(1):56. doi: 10.1186/s43074-026-00277-9. Epub 2026 Aug 14. PMID: 42603887; PMCID: PMC13476302.
- Ni, Y., Strohmer, T. Auto-Calibration and Biconvex Compressive Sensing with Applications to Parallel MRI. J Fourier Anal Appl 32, 32 (2026). https://doi.org/10.1007/s00041-025-10223-1
- Z. Zhang, S. Liu, M. Zhao, W. Zhou, A. Fu, S. Ghiasi, V. J. Srinivasan, and W. Yang, "Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.4.
- R. R. Joarder, W. Yang, V. J. Srinivasan, and S. Ghiasi, "DIGSS: Depth Isolation via Gating and Signal Separation — A Simulation Study of Pulsatile Time-Domain NIRS," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper TS4D.3.
- Fereidouni F, Ju W, Rezapourdamanab S, Sayrafi D, Hassan MA, Weyers B, Zhou X, Bec J, Gui D, Birkeland A, Marcu L. Effects of surgical resection on tissue autofluorescence lifetime signatures in head and neck cancer: implications for intraoperative tumor margin assessment. J Biomed Opt. 2026 Sep;31(9):096002. doi: 10.1117/1.JBO.31.9.096002. Epub 2026 Sep 4. PubMed PMID: 42699387; PubMed Central PMCID: PMC13544624.
- Zhou L, Yuan N, Hassan MA, Kraft L, Ehrlich K, Weyers BW, Ivanovic V, Raslan OAA, Gui D, Abouyared M, Bewley AF, Birkeland AC, Farwell DG, Marcu L, Qi J. Multimodal Fusion of Intraoperative FLIm and Preoperative PET/CT for Patient-Level Prediction of Lymph Node Metastasis in Head and Neck Cancer. Cancers (Basel). 2026 Jul 4;18(13). doi: 10.3390/cancers18132154. PubMed PMID: 42449696; PubMed Central PMCID: PMC13359770.
- Zhou X, Marcu L.Intravascular Fluorescence Lifetime Imaging: from Bench to Catheterization Lab. Curr Treat Options Cardio Med 28, 24 (2026). https://doi.org/10.1007/s11936-026-01155-0
- Saffarpour M, Li Z, Vali K, Qian W, Kasap B, Ghiasi S. DHF: A Generative AI Approach to Data-Efficient Signal Separation for Wearable Embedded Systems. ACM Trans. Embed. Comput. Syst. 25, 5, Article 86 (September 2026), 22 pages. https://doi.org/10.1145/3820374
- Ozcan A, Skala MC, Pogue BW, Popp J, Marcu L, Clancy CE. Optical digital twins for disease prevention, diagnosis, therapy, and intervention. J Biomed Opt. 2026 Aug;31(8):080601. doi: 10.1117/1.JBO.31.8.080601. Epub 2026 Aug 5. Review. PubMed PMID: 42559365; PubMed Central PMCID: PMC13440430.
- Wang Y, Yang X, Shen CY, Dong S, Pillar N, Ozcan A. Universal and transferable attacks on pathology foundation models using microscopic perturbations. Light Sci Appl. 2026 Jun 1;15(1). doi: 10.1038/s41377-026-02347-w. PubMed PMID: 42225639; PubMed Central PMCID: PMC13226705.
Preprint Archives
- Nobel Anbunesan S, Hassan MA, Qi J, Kraft L, Lee HS, Bloch O, et al. A Data-Centric Framework for Intraoperative Fluorescence Lifetime Imaging for Glioma Surgical Guidance. ArXiv. 2026 Apr 28. Available from: http://arxiv.org/abs/2604.26147
- Xu S, Liu J, Wang SH, Broecker S, Huang Y, Wang B, and Strohmer T. CyclOT: Learning Quadratic Optimal Transport Maps via Synchronized Forward–Backward Interpolants, ArXiv. 2026 Sept 12. Available from: https://arxiv.org/html/2609.13892v1
- Broecker S, Adams JY, Kumar G, Callcut RA, Ni Y, Strohmer T. Multimodal Deep Learning for ARDS Detection. medRxiv. 2026 Aug 12. Available from: https://www.medrxiv.org/content/10.1101/2025.08.08.25333333v1
- Liu R, Ranganathan V, Dahlbom D, Xu S, Zhang T, Ni Y, Pajerowski DM, Granroth G, Strohmer T, Stone MB, May AF. Observation geometry for uncertainty-aware Hamiltonian inference and experimental design in quantum magnets. ArXiv. 2026 Aug 11. Available from: https://arxiv.org/html/2608.10350v1
- Xu S, Strohmer T. Machine unlearning via information theoretic regularization. ArXiv 2026 Jul 6. Available from: https://arxiv.org/abs/2502.05684
- Xu S, Ni Y, Broecker S, Strohmer T. Forgetting-MarI: LLM unlearning via marginal information regularization. ArXiv. 2026 Jan 17. Available from: https://arxiv.org/abs/2511.11914
- Broecker S, del Rosario M, Selitser B, Strohmer T. The “I Don’t Know” Filter: Enhancing Agentic Reliability in Function Calling. ArXiv. 2026 Jul 4. Available from: https://arxiv.org/abs/2607.04034
Conference Abstracts/Presentations
- Ahamed A, Rawat A, Marcu L, Islam MS. Photon-trapping surface structures in ultrafast photodetectors: overcoming hardware limits with AI-driven computational imaging. Proc SPIE. 2026 Mar;13899:1389902.
- McPhillips LN, Rawat A, Ponizovskaya-Devine E, Islam MS. Boosting pixel efficiency through metasurfaces in deadspace regions. Proc SPIE. 2026 Mar;13908:67–73.
- Ahamed A, Myat H, Islam MS. AI-assisted hyperspectral imaging for narrow-band lasers using photon-trapping silicon photodiodes. Proc SPIE. 2026 Mar;13902:69–75.
- Islam MS. Photon-trapping single-photon detectors: enabling precision sensing beyond conventional limits. Invited paper presented at: SPIE Photonics West; 2026 Jan 22; San Francisco, CA. Paper 13920-136.
- Adams A. Fluorescence properties of collagen types I-V: a comprehensive spectral and lifetime analysis. Presented at: SPIE Photonics West Conference; 2026 Jan 21; San Francisco, CA. Conference 13855.
- Ahamed A, Myat H, Islam MS. AI-assisted hyperspectral imaging for narrow-band lasers using photon-trapping silicon photodiodes. Presented at: SPIE Photonics West; 2026 Jan 20; San Francisco, CA. Paper 13902-23.
- Ahamed A, Islam MS. Quantum true random number generator based on photon-trapping avalanche photodiodes. Presented at: SPIE Photonics West; 2026 Jan 18; San Francisco, CA. Paper 13919-12.
- Islam MS. Photon-trapping surface structures in ultrafast photodetectors: overcoming hardware limits with AI-driven computational imaging. Invited paper presented at: SPIE Photonics West; 2026 Jan 18; San Francisco, CA. Paper 13899-2.
- Kristen C. Dual-modality fluorescence lifetime imaging and polarization sensitive optical coherence tomography system for optical biopsy in brain. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13859.
- Ouyang X. Identification and Characterization of Biochemical and Morphological Markers of Atherosclerotic Plaque Progression Using Integrated FLIm-PSOCT Imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13826.
- Zhou X. Label-free characterization of human coronary arteries plaques via high-resolution laser scanning multispectral fluorescence lifetime imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13826.
- Adams A. Fluorescence lifetime sensitivity to immune infiltration during glioma resection. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13838.
- Adams A. Real-time spatial augmentation of fluorescence lifetime imaging on preoperative MRI for brain tumor resection guidance. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13838.
- Bec J. Rapid discrimination of high-grade prostate cancer using label-free fluorescence lifetime measurement in biopsy specimens. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13824.
- Hassan MA. EdgeWise: Real-time margin mapping in head-and-neck cancer with label-free fluorescence-lifetime imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13825.
- Thrapp A. Combined fluorescence lifetime imaging and interferometric near infrared spectroscopy for burn assessment. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13841.
- Zhang Z, Liu SJ, Zhao M, Zhou W, Fu A, Ghiasi S, et al. Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment. Optica Biophotonics Congress. Accepted 2026.
- Zhao M, Srinivasan VJ. Improving the time-of-flight filter in highly parallel interferometric diffusing wave spectroscopy (iDWS). Clinical and Translational Neurophotonics 2026. Proc SPIE. 2026 Mar 5; 13834:138340F. doi:10.1117/12.3081261.
- Thrapp A, Samanta R, Liu X, et al. Combined fluorescence lifetime imaging and speckle modulation interferometric near infrared spectroscopy for burn assessment. Multimodal Biomedical Imaging XXI. Proc SPIE. 2026 Mar 6; PC13841:PC1384108. doi:10.1117/12.3083349.
- Joarder R, Yang W, Srinivasan VJ, Ghiasi S. DIGSS: Depth Isolation via Gating and Signal Separation — a Simulation Study of Pulsatile Time-Domain NIRS. Biophotonics Congress. 2026; paper TS4D.3.
- Samanta R, Zhou W, Srinivasan VJ. Free-Space Interferometric Diffusing Wave Spectroscopy With an 8-bit Camera. Optica Biophotonics Congress: Biomedical Optics 2026 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.3
- Wang Z, Xuan X, Ma KL. Interactive Surgical Visualization with Real-Time Endoscopic Scene Reconstruction and Functional Imaging Overlay. Presented at: 2026 IEEE 23rd International Symposium on Biomedical Imaging; 2026.
- Z. Zhang, S. Liu, M. Zhao, W. Zhou, A. Fu, S. Ghiasi, V. J. Srinivasan, and W. Yang, "Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.4.
Invited Talks
- Marcu L. Interventional FLIM: What it takes to move from bench to operating theater. Presented at: BIOS 2026, SPIE Photonics West; 2026 Jan; San Francisco, CA.
- Alfonso Garcia, A., Optical spectroscopy for minimally invasive assessment of colorectal inflammation and polyp phenotyping. Presented at: Western Colorectal Cancer Consortium Conference; 2026 Oct 1; Davis, CA
- Srinivasan VJ. Seeing more with visible light: anatomy and color in aging and age-related macular degeneration. Invited talk presented at: Casey Eye Institute; 2026 Mar 2; Portland, OR.
- Srinivasan VJ. Seeing more with visible light OCT: anatomy and color in aging and age-related macular degeneration. Invited talk presented at: OSU Optometry Research Seminar; 2026 Jul 7; Columbus, OH.
- Srinivasan VJ. Seeing more with visible light OCT: retinal aging as a precursor to AMD and other forms of neurodegeneration. Invited talk (Hirsch Symposium) presented at: American Academy of Optometry (AAO); 2026 Oct 1; Anaheim, CA.
- A. Ozcan, "The Fusion of AI and Optics for Computational Microscopy and Sensing", Northwell Health Laboratories, Faculty Development Lecture Series, September 8, 2026 - Virtual
- A. Ozcan, " Virtual Histological Staining," CNSI Advanced Light Microscopy Symposium, California NanoSystems Institute (CNSI), University of California, Los Angeles, UCLA, May 15, 2026, Los Angeles, CA, USA (Keynote Talk)
- A. Ozcan, "Virtual Staining of Label-free Tissue Using Deep Learning," 12th Digital Pathology & AI Congress, May 7, 2026, Columbus, OH, USA (Keynote Talk)
- A. Ozcan, "Virtual Staining of Label-free Tissue," Ohio State University (OSU) Cancer Biology Research Program Retreat, May 6, 2026, Columbus, OH, USA (Keynote Talk)
- A. Ozcan, "Virtual Staining of Label-free Tissue," UCLA-Caltech NIH T32 Program Symposium, April 27, 2026, Los Angeles, CA, USA
- A. Ozcan, "The Fusion of AI and Optics for Computational Microscopy and Sensing", Beckman Laser Institute Seminar Series, University of California, Irvine, April 23, 2026, Irvine, CA, USA
- A. Ozcan, "The Fusion of AI and Optics for Computational Microscopy & Sensing in Low-resource Settings", NIH Research and Innovation Translation Partnerships Conference and Technology Showcase: Point of Care Technologies and Digital Health, NIH, April 21, 2026, Bethesda, MD, USA
- A. Ozcan, "The Fusion of AI and Optics for Computational Microscopy and Sensing", University of Texas at Austin, Department of Electrical and Computer Engineering Colloquium, April 15, 2026, Austin, TX, USA
- A. Ozcan, "Virtual Staining of Label-Free Tissue: Toward Data-Driven Digital Twins of Histology", SPIE Photonics West, Digital Twins as New Approach Methodologies in Biophotonics, January 18, 2026, San Francisco, CA, USA
- A. Ozcan, "Virtual staining of label-free tissue using deep learning", SPIE Photonics West, Advanced Chemical Microscopy for Life Science and Translational Medicine, January 17, 2026, San Francisco, CA, USA
- Qi J. Image reconstruction for positronium lifetime tomography, Symposium on AI and Reconstruction for Biomedical Imaging, London, UK, March 9, 2026
- Qi J. From PALS to PLT: Randoms-Limited Precision and Activity Optimization for Positronium Lifetime Tomography. The 6th Jagiellonian Symposium on Advances in Particle Physics and Medicine, Krakow, Poland, July 6, 2026.
- T. Strohmer. How Geometry Governs Privacy: The Entropic Scale. Plenary Talk, Foundations of Computational Mathematics, Vienna (Austria), July 2026.
- T. Strohmer. Can AI Truly Forget? A Mathematical Framework for Machine Unlearning. Foundations of Computational Mathematics, Vienna (Austria), July 2026.
- T. Strohmer. Can AI Truly Forget? A Mathematical Framework for Machine Unlearning. Stanford University, January 2026.
- J. Lie. CyclOT: Learning Quadratic Optimal Transport Maps via Synchronized Forward–Backward Interpolant. Duke Summer school on Machine Learning, August 2026.
- S. Broecker. The “I Don’t Know” Filter: Enhancing Agentic Reliability in Function Calling. Agentic AI Summit 2026
2025 Publications
Journal Papers & Peer Reviewed Proceedings
- Alfonso-Garcia A, Bec J, Hassan MA, Noble Anbunesan S, Kraft L, Bobinski M, et al. Label-free fluorescence lifetime imaging for real-time guidance of stereotactic biopsy: A feasibility study in brain cancer patients. Neurooncol Adv. 2025;7(1):vdaf172. doi:10.1093/noajnl/vdaf172 PubMed PMID: 41104039. PMCID: PMC12527272
- Baldini F, Dholakia K, French P, Guntinas-Lichius O, Kohler A, Mäntele W, et al. Shining a Light on the Future of Biophotonics. J Biophotonics. 2025 Jul;18(7):e202500148. doi:10.1002/jbio.202500148 PubMed PMID: 40364668. PMCID: PMC12245495
- Dave DR, Alfonso Garcia A, Kraft L, Marcu L, Pereira CT. Defining the Zone of Acute Peripheral Nerve Injury Using Fluorescence Lifetime Imaging in a Crush Injury Sheep Model. J Hand Surg Am. 2025 Oct;50(10):1277.e1-1277.e7. doi:10.1016/j.jhsa.2024.11.020 PubMed PMID: 39755964. PMCID: PMC12226729
- Devine EP, Yamada T, Wang SY, Islam MS. Stacked co-packaged Si-Ge-Si photodetectors with > 60 GHz bandwidth for near-infrared wavelength-simulation. Discover Electronics. 2025;2(1):99. doi:10.1007/s44291-025-00137-z
- Georgakoudi I, Skala MC, Quinn KP, Stringari C, Sorrells JE, Heikal AA, et al. Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling. J Biomed Opt. 2025 Feb;30(Suppl 2):S23901. doi:10.1117/1.JBO.30.S2.S23901 PubMed PMID: 41230436. PMCID: PMC12604823
- Hassan MA, Sun P, Zhou X, Kraft L, Hadfield KT, Ehrlich K, et al. Data-Centric Learning Framework for Real-Time Detection of Aiming Beam in Fluorescence Lifetime Imaging Guided Surgery. IEEE Trans Biomed Eng. 2025 Oct;72(10):2972–80. doi:10.1109/TBME.2025.3557376 PubMed PMID: 40232904.
- Liu F, Li X. Effectiveness of digital dispersion compensation in OCT. Biomed Opt Express. 2025 Aug 1;16(8):3017–26. doi:10.1364/BOE.567257 PubMed PMID: 40809972. PMCID: PMC12339299
- Liu X, Bec J, Zhou X, Garcia AA, Marcu L. Multispectral laser-scanning pulse-sampling fluorescence lifetime system for large-scale tissue imaging. Opt Lett. 2025 Feb 1;50(3):900–3. doi:10.1364/OL.547582 PubMed PMID: 39888783. PMCID: PMC12091187
- Ray S, Lee CY, Park HC, Nauen DW, Bettegowda C, Li X, et al. Leveraging pretrained vision transformers for automated cancer diagnosis in optical coherence tomography images. Biomed Opt Express. 2025 Aug 1;16(8):3283–94. doi:10.1364/BOE.563694 PubMed PMID: 40809960. PMCID: PMC12339304
- Schoop RAL, de Roode LM, Alfonso-García A, Fereidouni F, de Boer LL, Marcu L, et al. Phasor theory of fluorescence lifetime imaging utilized on a maximum range of frequencies for prostate tissue analysis. Biomed Opt Express. 2025 Nov 1;16(11):4885–901. doi:10.1364/BOE.575841 PubMed PMID: 41293707. PMCID: PMC12642976
- Qian W, Saffarpour M, Joarder RR, Kasap B, Vali K, Lihe T, et al. Non-invasive detection of instantaneous fetal hypoxemia in large animal model of pregnancy. NPJ Biomed Innov. 2025; 2(1):12. doi:10.1038/s44385-025-00014-0. PubMed PMID: 40290857; PMCID: PMC12018256.
- Majeski JB, Forti RM, Chong SH, Aparanji S, Zhao M, Abramson K, et al. Comparison of diffuse correlation spectroscopy, interferometric diffusing wave spectroscopy, and speckle contrast optical spectroscopy for blood flow monitoring. Neurophotonics. 2025 Jul;12(3):035005. doi:10.1117/1.NPh.12.3.035005. PubMed PMID: 40799972; PMCID: PMC12340614.
- Mazumder D, Aparanji S, Kholiqov O, Hamilton D, Samanta R, Srinivasan VJ. 1060 nm interferometric near-infrared spectroscopy. Opt Lett. 2025 Apr 1;50(7):2382–5. doi:10.1364/OL.558899. PubMed PMID: 40167726; PMCID: PMC12286623
- Zhao M, Dickstein L, Nadig AS, Zhou W, Aparanji S, Estrada HG, et al. Comprehensive Optimization of Interferometric Diffusing Wave Spectroscopy (iDWS). IEEE J Sel Top Quantum Electron. 2025 Jul-Aug;31(4):7400513. doi:10.1109/JSTQE.2025.3537642. PubMed PMID: 41822112; PMCID: PMC12978398.
- Gupta AK, Meng R, Duelk M, Wald K, Srinivasan VJ. High-resolution visible light OCT of the human retina with combined superluminescent diodes. Opt Lett. 2025 Jun 15;50(12):4070–3. doi:10.1364/OL.560148. PubMed PMID: 40512945; PMCID: PMC12306631.
- Meng R, Gupta AK, Kho A, Srinivasan VJ. Imaging melanin-associated organelles in the retinal pigment epithelium via visible light OCT redshift. Opt Lett. 2025 Jan 15;50(2):475–8. doi:10.1364/OL.542497. PubMed PMID: 39815540; PMCID: PMC12258066.
- Xuan X, Ono JP, Gou L, Ma KL, Ren L. AttributionScanner: A Visual Analytics System for Model Validation With Metadata-Free Slice Finding. IEEE Trans Vis Comput Graph. 2025 Oct;31(10):7436–47. PubMed PMID: 40031557; PMCID: PMC12490708.
- Xuan X, Wang X, He W, Ono JP, Gou L, Ma KL, et al. VISTA: A Visual Analytics Framework to Enhance Foundation Model-Generated Data Labels. IEEE Trans Vis Comput Graph. 2025 Oct;31(10):6991–7003. PubMed PMID: 40031290; PMCID: PMC12490709.
- Fanous MJ, Seybold CM, Chen H, Pillar N, Ozcan A. BlurryScope enables compact, cost-effective scanning microscopy for HER2 scoring using deep learning on blurry images. NPJ Digit Med. 2025 Aug 6;8(1):506. doi:10.1038/s41746-025-01882-x. PubMed PMID: 40764388; PMCID: PMC12325710.
- Zhang Y, Huang L, Pillar N, Li Y, Li Y, Migas LG, et al. Virtual staining of label-free tissue in imaging mass spectrometry. Sci Adv. 2025 Aug;11(31):eadv0741. doi:10.1126/sciadv.adv0741. PubMed PMID: 40749063; PMCID: PMC12315973.
- Li Y, Pillar N, Liu T, Ma G, Qi Y, de Haan K, et al. Label-Free Evaluation of Lung and Heart Transplant Biopsies Using Tissue Autofluorescence-Based Virtual Staining. BME Front. 2025;6:0151. doi:10.34133/bmef.0151. PubMed PMID: 40606521; PMCID: PMC12217214.
- Zhang Y, Huang L, Pillar N, Li Y, Chen H, Ozcan A. Pixel super-resolved virtual staining of label-free tissue using diffusion models. Nat Commun. 2025 May 30;16(1):5016. doi:10.1038/s41467-025-60387-z. PubMed PMID: 40447613; PMCID: PMC12125245.
- Zhou L, Yuan N, Ehrlich K, Qi J. NCF: neural correspondence field for medical image registration. Proc SPIE. 2025; 13406:134062G. doi:10.1117/12.3047329.
- He, Y., Strohmer, T., Vershynin, R. & Zhu, Y. Differentially private low-dimensional synthetic data from high-dimensional datasets, Information and Inference: A Journal of the IMA, Volume 14, Issue 1, March 2025, iaae034, https://doi.org/10.1093/imaiai/iaae034
- Boedihardjo M, Strohmer T, Vershynin R. Covariance loss, Szemerédi regularity, and differential privacy. Proc Am Math Soc. 2025. PubMed PMID: 40766847; PMCID: PMC12323573.
Preprint Archives
- Hassan MA, Kraft L, Azam MA, Bec J, Hadfield KT, Qi J, et al. Enhancing Label-Free Fluorescence Lifetime Imaging for Intraoperative Tumor Margin Delineation in Head and Neck Cancer using Data-Centric AI. Res Sq. 2025 May 23;rs.3.rs-6673642. doi:10.21203/rs.3.rs-6673642/v1 PubMed PMID: 40470246. PMCID: PMC12136734
- Yang X, Aydin M, Lu Y, Selcuk SY, Bai B, Zhang Y, et al. Autonomous labeling of surgical resection margins using a foundation model. ArXiv. 2025 Nov 27. PubMed PMID: 41356060. Available from: http://arxiv.org/abs/2511.22131
Conference Abstracts/Presentations
- Zhou X, et al. Combined multispectral FLIm/polarization-sensitive OCT catheter system for detection of macrophage foam cells in human atherosclerotic lesions. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Sun P, et al. Dynamic real-world scaling for enhanced PS-FLIm data visualization in TORS. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Hassan M, et al. Data-centric learning framework for real-time surgical guidance using fiber-based FLIm. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Liu X, et al. Multispectral pulse-sampling fluorescence lifetime imager for high-speed large-scale tissue imaging. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Adams A, Alfonso-Garcia A, Anbunesan SN, Bec J, Lee HS, Bloch O, et al. Enhanced In Vivo Detection of Glioblastoma’s Infiltrative Edge Using FLIm. Optica Biophotonics Congress 2025, Technical Digest Series. 2025; paper TW2F.5.
- Vali K, Kasap B, Vafi A, Ghiasi S. JOIN: Optimized Light Source Activation for Deep Tissue Optical Sensing. Presented at: IEEE/ACM International Conference on Cyber-Physical Systems; 2025.
- Fowler R, Kasap B, Joarder R, Ghiasi S. Non-invasive Fetal Blood pH Estimation for Enhanced Intrapartum Monitoring using Near-Infrared Spectroscopy. Presented at: Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 2025.
- Lihe L, Qian W, Kasap B, Ghiasi S. PSAFE: Extraction of Faint Fetal PPG from Non-Invasively Acquired Mixed PPG Signals. Presented at: IEEE Body Sensor Networks; 2025.
- Qian W, Joarder R, Fowler R, Kasap B, Saffarpour M, Ghiasi S. Blind Source Separation for Fetal PPG with Rate-Based Proxy Supervision. Presented at: NeurIPS Workshop on Learning from Time Series for Health; 2025.
- Aparanji S, Zhao M, Nadig A, Estrada HG, Hamilton D, Srinivasan VJ. Time-of-flight filtered long wavelength interferometric diffusing wave spectroscopy. Clinical and Translational Neurophotonics 2025. Proc SPIE. 2025; PC133020B.
- Mazumder D, Aparanji S, Kholiqov O, Hamilton D, Estrada HG, Samanta R, et al. Interferometric near-infrared spectroscopy (iNIRS) at 1060 nm. Clinical and Translational Neurophotonics 2025. Proc SPIE. 2025; PC133020D.
- Samanta R, Mazumder D, Kholiqov O, Srinivasan VJ. Dynamic speckle-modulated interferometric near-infrared spectroscopy of non-ergodic samples. Optics and the Brain. 2025; paper BW1B.2. Optica Publishing Group.
- Srinivasan VJ. High-throughput human cerebral blood flow monitoring with interferometric diffuse optics. High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond X. Proc SPIE. 2025; PC133300E.
- Srinivasan VJ. Interferometric diffuse optics: recent advances and future outlook. Computational Optical Imaging and Artificial Intelligence in Biomedical Sciences II. Proc SPIE. 2025; PC133330H.
- Meng R, Gupta AK, Srinivasan VJ. Optoretinography with visible light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2025; 66:4794.
- Meng R, Gupta AK, Srinivasan VJ. Quantifying Bruch’s membrane thickness in aging with visible light optical coherence tomography. Ophthalmic Technologies XXXV. Proc SPIE. 2025;PC133000C.
- Srinivasan V, Gupta A. Anatomically informed imaging and quantification of macular pigments in the living human eye with visible light Optical Coherence Tomography. J Alzheimers Dis. 2025.
- Chauhan P, Kho A, Srinivasan V. Inner nuclear layer sublamination in the mouse with visible light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2025;66:1501.
- Gupta AK, Meng R, Srinivasan V. A clinical visible light OCT system with superluminescent diodes (SLDs). Invest Ophthalmol Vis Sci. 2025; 66:1500.
- Xuan X, Deng Z, Ma KL. ReME: A Data-Centric Framework for Training-Free Open-Vocabulary Segmentation. Presented at: IEEE/CVF International Conference on Computer Vision; 2025.
- Malik D, Xuan X, Ma KL. Towards Interactive 3D Surgical Scene Reconstruction: an Incremental Training and Monitoring Framework. Presented at: 2025 IEEE 22nd International Symposium on Biomedical Imaging; 2025 Apr 14–17; Houston, TX.
- Wang Z, Xuan X, Ma KL. Interactive Surgical Visualization with Real-Time Endoscopic Scene Reconstruction and Functional Imaging Overlay. Presented at: 2025 IEEE 23rd International Symposium on Biomedical Imaging; 2025 Apr 8–11; Houston, TX.
- Zhou L, Yuan N, Qi J. NCF: Neural Correspondence Field for Medical Image Registration. Presented at: SPIE Medical Imaging Symposium, Imaging Processing Conference; 2025 Feb; San Diego, CA.
Invited Talks
- Marcu L. Fluorescence Lifetime Imaging in Clinical Interventions. Invited seminar presented at: Wyant College of Optical Sciences; 2025 Dec 4; Tucson, AZ.
- Marcu L. Advancing Interventional Cardiology with Label-Free Fluorescence Lifetime Imaging. Keynote lecture presented at: BioPhotonics Conference 2025; 2025 Oct 16.
- Alfonso-Garcia A. Label-free imaging of gastrointestinal disease. Presented at: 16th Annual UC Davis Research Retreat on Host-Microbe Interaction; 2025 Oct 10; Granlibakken, CA.
- Alfonso-Garcia A. Intraluminal FLIm assessment of gastrointestinal inflammation. Presented at: SCIX 2025; 2025 Oct 7; Covington, KY.
- Marcu L. Data-Centric Approach to FLIM for Intraoperative Head and Neck Cancer Margin Detection. Invited talk presented at: SCIX 2025; 2025 Oct 5–10; Covington, KY.
- Marcu L. Label-Free FLIM in Surgical Oncology. Keynote lecture presented at: World Molecular Imaging Congress; 2025 Sep 29–Oct 3; Anchorage, AK.
- Marcu L. Next-Generation Cardiovascular Imaging: The Role of FLIM and OCT. Invited talk presented at: 1st Carpathian Biophotonics Meeting; 2025 Sep 8–12; Sinaia, Romania.
- Marcu L. Interventional FLIM. Invited talk presented at: Center for Biophotonic Technology and Artificial Intelligence, University at Albany, SUNY; 2025 Jul 31.
- Islam S. AI-Driven Nanophotonic Imaging on a CMOS Platform: Precision, Speed, and Miniaturization. Invited talk presented at: IEEE International Conference on Optical MEMS and Nanophotonics; 2025 Jul 13–18; Chiang Mai, Thailand.
- Islam S. AI-Powered Nanosystems-on-a-Chip for Imaging and Sensing: Unlocking New Dimensions of Insight. Invited lecture presented at: University of Dhaka; 2025 Jul 7; Dhaka, Bangladesh.
- Marcu L. Fluorescence Lifetime Imaging in the Operating Theater. Invited seminar presented at: DTU Health Tech; 2025 Jun 17; Denmark.
- Marcu L. Biophotonics Summer School 2025. Lecturer, 4 lectures. Presented at: 12th International Graduate Summer School; 2025 Jun 7–14; Island of Ven, Sweden.
- Alfonso-Garcia A. Fluorescence lifetime imaging for disease detection and surgical guidance. Presented at: CLEO 2025; 2025 May 5; Long Beach, CA.
- Marcu L. FLIM in Neurosurgery. Invited talk presented at: OPTICA Biophotonics Congress; 2025 Apr 21–24; Coronado, CA.
- Marcu L. National Center for Interventional Biophotonic Technologies: An Overview. Invited talk presented at: Center for Label-Free Imaging and Multiscale Biophotonics Annual Symposium; 2025 Apr; University of Illinois Urbana-Champaign.
- Li XD. Low-coherence Biophotonics Imaging for the Brain. Invited seminar presented at: UC Irvine Beckman Laser Institute & Medical Clinic; 2025 Mar 27; Irvine, CA.
- Li XD. Two-photon fiberscopy for neuronal imaging in freely moving rodents. Invited talk presented at: SPIE Photonics West, Neural Imaging and Sensing Conference; 2025 Jan 27; San Francisco, CA. Conference 13303.
- Li XD. Low-coherence Biophotonics Imaging for the Brain. Invited seminar presented at: Geisel School of Medicine at Dartmouth and Thayer School of Engineering; 2025 Jan 9; Hanover, NH.
- Marcu L. Pulse-sampling FLIM in medical applications. Keynote lecture presented at: BIOS 2025, SPIE Photonics; 2025 Jan; San Francisco, CA.
- Marcu L. FLIM-guided surgical interventions. Invited talk presented at: BIOS 2025, SPIE Photonics; 2025 Jan; San Francisco, CA.
- Ma KL. Advancing AI Scaling towards the Open World: Efficiency, Responsibility, and Adaptability. Presented at: Computer Science Colloquium, University of Arizona; 2025 Nov 15; Tucson, AZ.
- Qi J. Do not throw away imaging physics in the age of AI. Edward J Hoffman Award presentation at: IEEE Medical Imaging Conference; 2025 Nov 6.
- Ma KL. AI-Assisted and Human-Centered Approaches to Visualization Design. Keynote presented at: Visual Computer Trend 2025; 2025 Jan 30; Tech Gate Vienna, Austria.
- A. Ozcan, "Virtual staining of label-free tissue," Annual Rice University Center for Nanoscale Imaging Sciences Conference, Rice University, November 18, 2025, Houston, TX, USA (Keynote Talk)
- Srinivasan VJ. Interferometric diffuse optics: recent advances and future outlook. Plenary/Hot Topics talk presented at: SPIE Photonics West; 2025 Jan 25; San Francisco, CA.
- Srinivasan VJ. High-throughput human cerebral blood flow monitoring with interferometric diffuse optics (Invited Paper). Invited talk presented at: SPIE Photonics West; 2025 Jan 25; San Francisco, CA.
- Srinivasan VJ. Invited talk presented at: Oculomics Session; 2025 May; Salt Lake City, UT.
- Srinivasan VJ. Anatomically informed imaging and quantification of macular pigments in the living human eye with visible light optical coherence tomography. Invited talk presented at: Brain and Ocular Nutrition (BON) Conference; 2025 Jun 19; Beverly, MA.
2024 Publications
Journal Papers & Peer Reviewed Proceedings
- Ahamed A, Rawat A, McPhillips LN, Mayet AS, Islam MS. Unique Hyperspectral Response Design Enabled by Periodic Surface Textures in Photodiodes. ACS Photonics. 2024 Jun 19;11(6):2497–505. doi:10.1021/acsphotonics.4c00453 PubMed PMID: 38911844. PMCID: PMC11191742
- Bec J, Zhou X, Villiger M, Southard JA, Bouma B, Marcu L. Dual modality intravascular catheter system combining pulse-sampling fluorescence lifetime imaging and polarization-sensitive optical coherence tomography. Biomed Opt Express. 2024 Apr 1;15(4):2114–32. doi:10.1364/BOE.516515 PubMed PMID: 38633060. PMCID: PMC11019710
- Hall G, Liang W, Bhujwalla ZM, Li X. SHG Fiberscopy Assessment of Collagen Morphology and Its Potential for Breast Cancer Optical Histology. IEEE Trans Biomed Eng. 2024 Aug;71(8):2414–20. doi:10.1109/TBME.2024.3372629 PubMed PMID: 38437141. PMCID: PMC11257778
- Park HC, Li D, Liang R, Adrales G, Li X. Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC) for Esophagus Surveillance and Interventions. BME Front. 2024 May 23;5:0041. doi:10.34133/bmef.0041 PubMed PMID: 38577399. PMCID: PMC10993155
- S. Mayet A, Das B, Afzal H, Zaman S, Ghandiparsi S, Dhar NK, et al. Finite-Difference Time-Domain Simulations of Photon-Trapping Nanohole Arrays for Enhanced Optical Absorption in Ultrahigh-Speed GaAs Photodetectors. ACS Appl Nano Mater. 2024 May 10;7(9):10037–45. doi:10.1021/acsanm.4c00257
- Tsubokawa M, Saif Islam M. Design of a metasurface deflector for guided absorption enhancement in a Si PIN photodiode. Opt Express. 2024 Jun 3;32(12):21121–33. doi:10.1364/OE.523755 PubMed PMID: 38859474.
- Tufaro V, Jaffer FA, Serruys PW, Onuma Y, van der Steen AFW, Stone GW, et al. Emerging Hybrid Intracoronary Imaging Technologies and Their Applications in Clinical Practice and Research. JACC Cardiovasc Interv. 2024 Sep 9;17(17):1963–79. doi:10.1016/j.jcin.2024.07.007 PubMed PMID: 39260958. PMCID: PMC11996234
- Yuan N, Hassan MA, Ehrlich K, Weyers BW, Biddle G, Ivanovic V, et al. Early Detection of Lymph Node Metastasis Using Primary Head and Neck Cancer Computed Tomography and Fluorescence Lifetime Imaging. Diagnostics (Basel). 2024 Sep 23;14(18):2097. doi:10.3390/diagnostics14182097 PubMed PMID: 39335776. PMCID: PMC11430879
- Kasap B, Vali K, Qian W, Mo L, Chithiwala ZH, Curtin AC, et al. Transcutaneous Discrimination of Fetal Heart Rate from Maternal Heart Rate: A Fetal Oximetry Proof-of-Concept. Reprod Sci. 2024 Aug;31(8):2331–41. doi:10.1007/s43032-024-01582-z. PubMed PMID: 38728001; PMCID: PMC11932717.
- Mazumder D, Kholiqov O, Srinivasan VJ. Interferometric near-infrared spectroscopy (iNIRS) reveals that blood flow index depends on wavelength. Biomed Opt Express. 2024 Apr;15(4):2152–74. doi:10.1364/BOE.507373. PubMed PMID: 38633063; PMCID: PMC11019706.
- Yang X, Bai B, Zhang Y, Aydin M, Li Y, Selcuk SY, et al. Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning. Nat Commun. 2024;15. doi:10.1038/s41467-024-52263-z. PubMed PMID: 39266547; PMCID: PMC11393327.
- Fanous MJ, Casteleiro Costa P, Isil C, Huang L, Ozcan A. Neural Network-Based Processing and Reconstruction of Compromised Biophotonic Image Data. Light Sci Appl. 2024. doi:10.1038/s41377-024-01544-9. PubMed PMID: 39237561; PMCID: PMC11377739.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling. BME Front. 2024;5:0048. doi:10.34133/bmef.0048. PubMed PMID: 39045139; PMCID: PMC11265840.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Virtual histological staining of unlabeled autopsy tissue. Nat Commun. 2024 Feb 23;15(1):1684. doi:10.1038/s41467-024-46077-2. PubMed PMID: 38396004; PMCID: PMC10891155.
- Pillar N, Li Y, Zhang Y, Ozcan A. Virtual Staining of Nonfixed Tissue Histology. Mod Pathol. 2024;37:100444. doi:10.1016/j.modpat.2024.100444. PubMed PMID: 38325706; PMCID: PMC11918264.
- Yuan N, Hassan MA, Ehrlich K, Weyers BW, Biddle G, Ivanovic V, et al. Early Detection of Lymph Node Metastasis Using Primary Head and Neck Cancer Computed Tomography and Fluorescence Lifetime Imaging. Diagnostics. 2024;14(18):2097. doi:10.3390/diagnostics14182097. PubMed PMID: 39335776.
- Sheng J, Strohmer T. Semi-Supervised Clustering of Sparse Graphs: Crossing the Information-Theoretic Threshold. J Mach Learn. 2024;3(1):64–106. Doi:10.4208/jml.230624. PMID: 39493625; PMCID: PMC11531408.
- Li Y, Wang J, Aboagye P, Yeh CM, Zheng Y, Wang L, et al. Visual Analytics for Efficient Image Exploration and User-Guided Image Captioning. IEEE Trans Vis Comput Graph. 2024 Jun;30(6):2875–87. doi:10.1109/TVCG.2024.3388514. PubMed PMID: 38625780; PMCID: PMC11412260.
Preprint Archives
- Saffarpour M, Vali K, Qian W, Kasap B, Hedriana HL, Ghiasi S. Deep Harmonic Finesse: Signal Separation in Wearable Systems with Limited Data. Proc Des Autom Conf. 2024 Jul 1. doi:10.1145/3649329.3657339. Available from: https://arxiv.org/abs/2407.01840
- He Y, Strohmer T, Vershynin R, Zhu Y. Differentially Private Low-dimensional Synthetic Data from High-dimensional Datasets. ArXiv. 2024 Dec 11. Available from: http://arxiv.org/abs/2305.17148
- Xu S, Strohmer T. WHOMP: Optimizing Randomized Controlled Trials via Wasserstein Homogeneity. ArXiv. 2024 Oct 3. Available from: http://arxiv.org/abs/2409.18504
- Xu S, Strohmer T. On the (In)Compatibility between Group Fairness and Individual Fairness. ArXiv. 2024 Jan 13. Available from: http://arxiv.org/abs/2401.07174
- Feng X, Strohmer T. Improving Autoencoder Image Interpolation via Dynamic Optimal Transport. ArXiv. 2024 Apr 13. Available from: http://arxiv.org/abs/2404.08900
- Kumar G, Strohmer T, Vershynin R. An Algorithm for Streaming Differentially Private Data. ArXiv. 2024 Jan 31. Available from: http://arxiv.org/abs/2401.14577
Conference Abstracts/Presentations
- Kekula Z, Rawat A, Islam MS. Sensitivity analysis of Si-avalanche photodiode for noise performance assessment. 2024 IEEE Nanotechnology Materials and Devices Conference. 2024 Oct;114–116.
- Alfonso-Garcia A, Kraft L, Zhou X, Bec J, Marcu L, Wei D, et al. Colorectal Polyp Assessment with Label-Free Fluorescence Lifetime Imaging. Optica Biophotonics Congress: Biomedical Optics 2024, Technical Digest Series. 2024; paper TM3B.2. doi:10.1364/TRANSLATIONAL.2024.TM3B.2.
- Ehrlich K, Hadfield KT, Hassan MA, Kraft L, Qi J, Gui D, et al. The Effect of Risk Factors on the Fluorescence Lifetime in Oropharyngeal Cancer. Optica Biophotonics Congress: Biomedical Optics 2024, Technical Digest Series. 2024; paper TTu3B.2. doi:10.1364/TRANSLATIONAL.2024.TTu3B.2.
- Bec J, et al. Demonstration of a combined multispectral FLIm/polarization-sensitive OCT catheter system for biochemical/structural evaluation of atherosclerosis lesions. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Bai Y, Rawat A, McPhillips LN, Islam MS. P-on-N versus N-on-P Silicon-Avalanche Photodiode Selection for Visible and Near Infrared Wavelength Applications. 2024 Device Research Conference. 2024; 1–2. doi:10.1109/DRC61706.2024.10605335.
- Rawat A, Islam SM. High-speed PiN photodiode design space exploration to break the speed-efficiency trade-off. Proc SPIE. 2024; 12880:194–200. doi:10.1117/12.3003413.
- Islam MS, Ahamed A, McPhillips LN, Rawat A. Precision photon manipulation in photodetectors for AI-driven ultrafast sensing and imaging. Proc SPIE. 2024; 12895: PC128950B. doi:10.1117/12.3007784.
- Alfonso-Garcia A, Lee JY, Condon A, Zhou X, Bec J, Baumler AJ, et al. Assessing in vivo label-free fluorescence lifetime imaging sensitivity to low-grade colon inflammation. Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases. 2024. doi:10.1117/12.3002008. Presented at: SPIE Photonics West 2024; 2024 Jan
- Ehrlich K, Hadfield KT, Kraft L, Hassan MA, Weyers BW, Zhou X, et al. Investigating fluorescence lifetime signatures for normal tissue adjacent to cancer in oropharyngeal squamous cell carcinomas. Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology. 2024. doi:10.1117/12.3003488. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Noble Anbunesan S, Alfonso-Garcia A, Bec J, Hassan M, Kraft L, Bobinski M, et al. Optical biopsy of brain tumors using fluorescence lifetime imaging. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems. 2024; PC1283101. doi:10.1117/12.3001898. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Hassan MA, Noble Anbunesan S, Alfonso-Garcia A, Bobinski M, Lee HS, Jin LW, et al. Detecting infiltrative edges of brain tumors using label-free intraoperative FLIm. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems. 2024; PC1283102. doi:10.1117/12.3003609. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Hassan MA, Weyers BW, Bec J, Qi J, Gui D, Bewley AF, et al. Mesoscopic FLIm for detection of residual cancer in transoral robotic surgery. Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology. 2024. doi:10.1117/12.2545150.6138709753001. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Ahamed A, Rawat A, McPhillips LN, Marcu L, Islam MS. On-chip hyperspectral detectors for fluorescence lifetime imaging. Proc SPIE. 2024; 12853:1285304. doi:10.1117/12.3002476. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Rawat A, Islam SM. Direction of arrival sensing enabled by introducing asymmetric surface structures in photodetectors. Proc SPIE. 2024; 12880:201–207. doi:10.1117/12.3003432.
- Islam MS, Rawat A, Tsubokawa M. Meta surface-enabled circular light propagation for ultra-fast and efficient photodetection. Proc SPIE. 2024; 13114:36–42. doi:10.1117/12.3030510.
- McPhillips LN, Rawat A, Ahamed A, Islam MS. DC linearity and absorption efficiency enhancement by introducing photon-trapping microstructures into avalanche photodetectors. Proc SPIE. 2024; 12895:90–96. doi:10.1117/12.3003649.
- Ahamed A, Rawat A, McPhillips LN, Wang SY, Islam MS. Scalable photodetector design with sub-picosecond response time. Proc SPIE. 2024; 12895:97–104. doi:10.1117/12.3002441. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Kobayashi NP, Talin AA, Davydov AV, Islam MS, editors. Low-Dimensional Materials and Devices 2024. Proc SPIE. 2024; 13114:1311401-1. doi:10.1093/oso/9780198517818.003.0004.
- Knapp T, Duan S, Alfonso-Garcia A, Merchant JL, Sawyer TW. Validation of label-free optical imaging markers of pancreatic cancer using spatial transcriptomics. Label-free Biomedical Imaging and Sensing. 2024; 12854:29–42. doi:10.1117/12.2691452.84be641d-5410-ee11-a99a-b38e0bc17c27.
- Ghiasi S. Deep Quasi-Periodic Priors: Signal Separation in Wearable Systems with Limited Data. Presented at: IEEE/ACM Design Automation and Test in Europe; 2024 Mar.
- Zhou W, Zhao M, Srinivasan VJ. A generalized form of the modified Siegert relationship. Presented at: Dynamics and Fluctuations in Biomedical Photonics XXI; 2024. Proc SPIE.
- Zhao M, Aparanji S, Srinivasan VJ. Recovering tissue properties with a time-of-flight informed interferometric diffusing wave spectroscopy (iDWS) system. Proc SPIE. 2024.
- Majeski JB, Chong SH, Ramachandran NR, Abramson K, Aparanji S, Zhao M, et al. Comparison of diffuse correlation spectroscopy, speckle contrast optical spectroscopy, and interferometric diffusing wave spectroscopy for blood flow monitoring. Proc SPIE. 2024.
- Joarder R, Yang W, Srinivasan VJ, Ghiasi S. Inverse Modeling Approach for Fetal Oxygen Saturation Estimation with Spatial Intensity. Optica Biophotonics Congress: Biomedical Optics 2024. 2024; paper JS4A.1.
- Majeski J, Forti R, Chong S, Ramachandran N, Abramson K, Aparanji S, et al. A Comparative Study of Blood Flow Monitoring Using Interferometric Diffusing Wave Spectroscopy, Speckle Contrast Optical Spectroscopy, and Diffuse Correlation Spectroscopy. Optical Tomography and Spectroscopy. 2024; Optica Publishing Group.
- Forti RM, Majeski J, Mason M, Weeks M, Ramachandran N, Abramson K, et al. Performance assessment methodologies for diffuse optical flow technologies. Optical Tomography and Spectroscopy. 2024; Optica Publishing Group.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep Learning Enables Virtual Histological Staining of Label-free Autopsy Tissue Sections. Presented at: Biomedical Engineering Society Annual Meeting; 2024 Oct 23–26; Baltimore, MD.
- Yang X, Selcuk SY, Bai B, Zhang Y, Li Y, Aydin M, et al. Deep learning-based HER2 Scoring of Breast Cancer Images Using Pyramid Sampling. Presented at: Biomedical Engineering Society Annual Meeting; 2024 Oct 23–26; Baltimore, MD.
- Xu S. Fair Data Representation for Machine Learning at the Pareto Frontier. Presented at: BIRS/CMO Workshop on Computational Harmonic Analysis in Data Science and Machine Learning; 2024 Sep; Oaxaca, Mexico.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep learning-enabled virtual staining of label-free autopsy tissue sections. Presented at: SPIE Optics and Photonics; 2024 Aug 18–22; San Diego, CA. Paper 13118-38.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Classification of HER2 score in breast cancer images using deep learning and pyramid sampling. Presented at: SPIE Optics and Photonics; 2024 Aug 18–22; San Diego, CA. Paper 13118-17.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep learning-enabled virtual staining of unlabeled autopsy tissue sections. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Yang X, Bai B, Zhang Y, Aydin M, Li Y, Selcuk SY, et al. Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Broecker S. Multimodal data analysis, with applications to ARDS diagnosis. Presented at: International Pediatric and Lifespan Data Science Conference; 2024 May; Anaheim, CA.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Virtual histological staining of label-free autopsy tissue sections via deep learning. Presented at: Optica Conference on Lasers and Electro-Optics; 2024 May 5–10; Charlotte, NC.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Deep Learning-Enabled Classification of HER2 Score in Breast Cancer Using Pyramid Sampling. Presented at: Optica Conference on Lasers and Electro-Optics; 2024 May 5–10; Charlotte, NC.
Invited Talks
- Srinivasan VJ. Computational imaging and monitoring with interferometric diffuse optics. Invited talk presented at: SPIE Photonics West, Computational Optics; 2024 Jan; San Francisco, CA.
- Srinivasan VJ. Unifying diffuse optics with interferometry. Invited talk presented at: Optica Biophotonics Congress, Diffuse Optics; 2024 Apr; Fort Lauderdale, FL.
- Ma KL. Reliable AI with Human-in-the-loop Enhancement. Keynote presented at: TAICHI Workshop on AIxHCI; 2024 Dec 21; Taipei, Taiwan.
- Ozcan A. Virtual staining of label-free tissue using deep learning. Keynote talk presented at: MicroTAS 2024, 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2024 Oct 14; Montreal, Canada.
- Ozcan A. Virtual staining of label-free tissue. Keynote talk presented at: BioImaging North America Community Congress; 2024 Sep 24; University of Wisconsin-Madison, Madison, WI.
- Ozcan A. Virtual staining of label-free tissue. Invited talk presented at: Optica Frontiers in Optics Conference; 2024 Sep 23; Denver, CO.
- Strohmer T. Towards Fairness in Machine Learning via Optimal Transport. Presented at: Foundations of Data Science and Machine Learning; 2024 Sep; UC Davis, Davis, CA.
- Strohmer T. Towards Fairness in Machine Learning via Optimal Transport. Presented at: NSF CompMath PI Meeting; 2024 Jul; University of Washington, Seattle, WA.
- Qi J. From SPLIT to SIMPLE: high-resolution statistical image reconstruction methods for positronium lifetime imaging. Presented at: 5th Jagiellonian Symposium on Advances in Particle Physics and Medicine; 2024 Jun 29–Jul 7; Krakow, Poland.
- Qi J. Exploring the fascinating time axis in PET. Edward Hoffman Memorial Lecture presented at: SNMMI Annual Meeting; 2024 Jun.
- Strohmer T. The Mathematics of Privacy and Synthetic Data. Colloquium presented at: Department of Mathematics, University of California, Santa Barbara; 2024 May; Santa Barbara, CA.
- Strohmer T. Privacy and the Digital Revolution: Toward Digital Twins in Health. Presented at: Digital Health and AI Symposium, UC Davis Health; 2024 Apr; Sacramento, CA.
- Strohmer T. Data Privacy, Synthetic Data, and Computer Vision. Tutorial presented at: WACV Tutorial on AI Governance and Data Protection for Computer Vision and Beyond; 2024 Jan; Hawaii.
2023 Publications
Journal Papers & Peer Reviewed Proceedings
- Ahamed A, Wang W, Rawat A, McPhillips LN, Ponizovskaya Devine E, Wang SY, et al. Advancing Multi-Dimensional Vision: AI-Driven Imaging Using Unique Photodetectors with Integrated Surface Nanostructures. Proc SPIE Int Soc Opt Eng. 2023 Aug 5;12651:1265104. doi:10.1117/12.2682104 PubMed PMID: 41769386. PMCID: PMC12949674
- Alfonso-Garcia A, Noble Anbunesan S, Bec J, Lee HS, Jin LW, Bloch O, et al. In vivo characterization of the human glioblastoma infiltrative edge with label-free intraoperative fluorescence lifetime imaging. Biomed Opt Express. 2023 May 1;14(5):2196–208. doi:10.1364/BOE.481304 PubMed PMID: 37206147. PMCID: PMC10191664
- Hassan MA, Weyers BW, Bec J, Fereidouni F, Qi J, Gui D, et al. Anatomy-Specific Classification Model Using Label-Free FLIm to Aid Intraoperative Surgical Guidance of Head and Neck Cancer. IEEE Trans Biomed Eng. 2023 Oct 1;70(10):2863–73. doi:10.1109/TBME.2023.3266678 PubMed PMID: 37043314. PMCID: PMC10833893
- Hassan MA, Weyers B, Bec J, Qi J, Gui D, Bewley A, et al. FLIm-Based in Vivo Classification of Residual Cancer in the Surgical Cavity During Transoral Robotic Surgery. Greenspan H, Madabhushi A, Mousavi P, Salcudean S, Duncan J, Syeda-Mahmood T, et al., editors. Med Image Comput Comput Assist Interv. 2023 Oct;14228:587–96. doi:10.1007/978-3-031-43996-4_56 PubMed PMID: 40810134. PMCID: PMC12349881
- Noble Anbunesan S, Alfonso-Garcia A, Zhou X, Bec J, Lee HS, Jin LW, et al. Intraoperative detection of IDH-mutant glioma using fluorescence lifetime imaging. J Biophotonics. 2023 Apr 1;16(4):e202200291. doi:10.1002/jbio.202200291 PubMed PMID: 36510639. PMCID: PMC10522274
- Wang N, Lee CY, Park HC, Nauen DW, Chaichana KL, Quinones-Hinojosa A, et al. Deep learning-based optical coherence tomography image analysis of human brain cancer. Biomed Opt Express. 2023 Jan 1;14(1):81–8. doi:10.1364/BOE.477311 PubMed PMID: 36698668. PMCID: PMC9842008
- Zhou X, Haudenschild AK, Li C, Marcu L. Multimodal fluorescence lifetime imaging and optical coherence tomography for longitudinal monitoring of tissue-engineered cartilage maturation in a preclinical implantation model. J Biomed Opt. 2023 Feb 1;28(2):026003. doi:10.1117/1.JBO.28.2.026003 PubMed PMID: 36818585.
- Zhou X, Bec J, Ehrlich K, Garcia AA, Marcu L. Pulse-sampling fluorescence lifetime imaging: evaluation of photon economy. Opt Lett. 2023 Sep 1;48(17):4578–81. doi:10.1364/OL.490096 PubMed PMID: 37656559. PMCID: PMC9932524.
- Zhao M, Zhou W, Aparanji S, Mazumder D, Srinivasan VJ. Interferometric diffusing wave spectroscopy imaging with an electronically variable time-of-flight filter. Optica. 2023 Jan 20;10(1):42–52. doi:10.1364/OPTICA.472471. PubMed PMID: 37275218; PMCID: PMC10238083.
- Zhou W, Zhao M, Srinivasan VJ. Interferometric diffuse optics: recent advances and future outlook. Neurophotonics. 2023;10(1):013502. doi:10.1117/1.NPh.10.1.013502. PubMed PMID: 36284601; PMCID: PMC9587754.
- Liu S, Lee Y, Pivetti C, Kulubya E, Wang A, Farmer D, et al. Recovering fetal signals transabdominally through interferometric near-infrared spectroscopy (iNIRS). Biomed Opt Express. 2023 Nov;14(11):6031–47. doi:10.1364/BOE.500898. PubMed PMID: 38021126; PMCID: PMC10659808.
- Vali K, Vafi A, Kasap B, Ghiasi S. BASS: Safe Deep Tissue Optical Sensing for Wearable Embedded Systems. ACM Trans Embed Comput Syst. 2023 Oct;22(5s):Article 122. doi:10.1145/3607916. PubMed PMID: 38264154; PMCID: PMC10805365.
- Kasap B, Vali K, Qian W, Saffarpour M, Fowler R, Ghiasi S. Robust Fetal Heart Rate Tracking through Fetal Electrocardiography (ECG) and Photoplethysmography (PPG) Fusion. 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). 2023;1–4. doi:10.1109/EMBC40787.2023.10341068.
- Joarder R, Kasap B, Ghiasi S. RT-TRAQ: An algorithm for real-time tracking of faint quasi-periodic signals in noisy time series. Smart Health. 2023;28:100392. doi:10.1016/j.smhl.2023.100392. PubMed PMID: 37974565; PMCID: PMC10653118.
- Aparanji S, Zhao M, Srinivasan VJ. Decoding diffuse light scattering dynamics in layered tissues: path length versus fluctuation time scale. Opt Lett. 2023 Nov 15;48(22):6056–9. doi:10.1364/OL.507162. PubMed PMID: 37966788; PMCID: PMC10935582.
- Kasap B, Vali K, Qian W, Saffarpour M, Ghiasi S. KUBAI: Sensor Fusion for Non-Invasive Fetal Heart Rate Tracking. IEEE Trans Biomed Eng. 2023 Jul;70(7):2193–202. doi:10.1109/TBME.2023.3238736. PubMed PMID: 37022063; PMCID: PMC10346940.
- Liu CC, Abdelhafez YG, Yap SP, Acquafredda F, Schirò S, Wong AL, et al. AI-Based Automated Lipomatous Tumor Segmentation in MR Images: Ensemble Solution to Heterogeneous Data. J Digit Imaging. 2023. PubMed PMID: 36854923; PMCID: PMC10287587.
- Fanous MJ, Pillar N, Ozcan A. Digital staining facilitates biomedical microscopy. Front Bioinform. 2023;3:1243663. doi:10.3389/fbinf.2023.1243663. PubMed PMID: 37564725; PMCID: PMC10411189.
- Li Y, Wang J, Dai X, Wang L, Yeh CM, Zheng Y, et al. How Does Attention Work in Vision Transformers? A Visual Analytics Attempt. IEEE Trans Vis Comput Graph. 2023 Jun;29(6):2888–900. doi:10.1109/TVCG.2023.3261935. PubMed PMID: 37027263; PMCID: PMC10290521.
- Li T, Xie Z, Qi W, Asma E, Qi J. Unsupervised deep learning framework for data-driven gating in positron emission tomography. Med Phys. 2023 Oct;50(10):6047–59. doi:10.1002/mp.16642. PubMed PMID: 37538038; PMCID: PMC10592231.
- Xu S, Strohmer T. Fair Data Representation for Machine Learning at the Pareto Frontier. J Mach Learn Res. 2023;24:331. PubMed PMID: 39440315; PMCID: PMC11494318.
Preprint Archives
N/A
Conference Abstracts/Presentations
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: Women in Photonics 2023; 2023 Nov.
- Hassan MA, et al. FLIm-Based in Vivo Classification of Residual Cancer in the Surgical Cavity During Transoral Robotic Surgery. Poster presented at: Cancer Center Symposium 2023; 2023 Oct.
- Hassan MA, et al. FLIm-Based in Vivo Classification of Residual Cancer in the Surgical Cavity During Transoral Robotic Surgery. Presented at: International Conference on Medical Image Computing and Computer-Assisted Intervention; 2023 Oct.
- Condon A, Alfonso-Garcia A, et al. Evaluation of the Sensitivity of Fluorescence Lifetime Imaging to Low-Grade Inflammation in an Ex Vivo Murine Model. Poster and oral presentation at: Annual UC Systemwide Bioengineering Symposium; 2023 Jun.
- Alfonso-Garcia A, et al. iFLIM: optical biopsy for colorectal cancer. Poster presented at: Cancer Center Symposium 2023; 2023 May.
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: UC Davis BMEGG Symposium; 2023 May.
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: Optica Biophotonics Congress 2023; 2023 Apr.
- Hassan MA, et al. Anatomy-specific classification models using FLIm for head and neck cancer surgical guidance. Presented at: SPIE Photonics West BiOS 2023; 2023 Mar.
- Zhou X, et al. Photon economy of pulse-sampling vs TCSPC fluorescence lifetime imaging. Presented at: SPIE Photonics West 2023; 2023 Mar.
- Noble SA, et al. Intraoperative detection of IDH-mutant glioma using fluorescence lifetime imaging. Presented at: SPIE Photonics West 2023; 2023 Mar.
- Kasap B, Vali K, Qian W, Mo L, Chithiwala ZH, Hedriana HL, et al. Use of A Novel Transabdominal Fetal Pulse Oximeter (TFO) In Human Pregnancy: A Proof-of-Concept. Am J Obstet Gynecol. 2023 Jan 1; 228(1):S100. doi:10.1016/j.ajog.2022.11.211
- Qian W, Vali K, Kasap B, Pivetti CD, Theodorou CM, Kulubya ES, et al. Continuous Transabdominal Fetal Pulse Oximetry (TFO) in Pregnant Ewe Models under Induced Fetal Hypoxia. Am J Obstet Gynecol. 2023; 228(1):S242–S3. doi:10.1016/j.ajog.2022.11.441.
- Aparanji S, Zhao M, Srinivasan VJ. Interferometric diffusing wave spectroscopy with an optical time-of-flight switch. Presented at: Dynamics and Fluctuations in Biomedical Photonics XX; 2023. Proc SPIE.
- Liu S, Lee Y, Pivetti C, Kulubya E, Wang A, Farmer D, et al. Transabdominal fetal signals measurement using fiber-based frequency-modulated continuous-wave near-infrared spectroscopy in a fetal lamb model. Biophotonics Congress: Optics in the Life Sciences 2023, Technical Digest Series. 2023; paper DW4A.6.
- Mazumder D, Kholiqov O, Srinivasan VJ. Dual-wavelength interferometric near-infrared spectroscopy (iNIRS). Bio-Optics: Design and Application. 2023; Optica Publishing Group.
- Zhao M, Zhou W, Aparanji S, Mazumder D, Srinivasan VJ. Interferometric diffusing wave spectroscopy imaging with an electronically variable time-of-flight filter. Proc SPIE. 2023.
- Ghiasi S. BASS: Safe Deep Tissue Optical Sensing for Wearable Embedded Systems. Presented at: IEEE/ACM International Conference on Hardware/Software Codesign and System Synthesis; Sept 2023.
- Kasap B. Robust Fetal Heart Rate Tracking through Fetal Electrocardiography (ECG) and Photoplethysmography (PPG) Fusion. Presented at: 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 2023.
- Joarder R. RT-TRAQ: An algorithm for real-time tracking of faint quasi-periodic signals in noisy time series. Presented at: IEEE/ACM International Conference on Connected Health: Applications, Systems and Engineering Technologies; 2023.
- Zhang Y, Huang L, Liu T, Cheng K, de Haan K, Li Y, et al. Neural network-based virtual staining of defocused autofluorescence images of label-free tissue. Presented at: Conference on Lasers and Electro-Optics; 2023;1–2.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Darrow MA, et al. Virtual HER2 staining of label-free breast tissue using autofluorescence imaging and deep learning. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI. Proc SPIE. 2023;PC12368:PC123680J. doi:10.1117/12.2648173.
- Ozcan A. Virtual staining of label-free tissue using deep learning. Presented at: Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI; 2023;PC1262207.
- Ozcan A. Overview on deep-learning-enabled computational microscopy and diffractive imaging. Presented at: Quantitative Phase Imaging IX; 2023. Proc SPIE. 2023;PC12389:PC1238901. doi:10.1117/12.2674088.
- Yang X, Bai B, Li Y, Zhang Y, Liu T, de Haan K, et al. Virtual stain-to-stain transformations via cascaded deep neural networks. Multimodal Biomedical Imaging XVIII. Proc SPIE. 2023;PC12371:PC123710C. doi:10.1117/12.2648101.
Invited Talks
- Marcu L. Fluorescence Lifetime Imaging in Clinical Interventions. Invited seminar presented at: University of California Los Angeles; 2023 Dec.
- Li XD. Low-coherence Biophotonics for the Brain. Invited seminar presented at: Institute of NanoEngineering and MicroSystems, National Tsing Hua University; 2023 Dec; Taiwan.
- Li XD. Low-coherence Biophotonics for the Brain. Invited seminar presented at: Department of Biomedical Engineering and Center for Translational Research, National Cheng Kung University; 2023 Dec; Taiwan.
- Harsh GA. Interventional fluorescence lifetime imaging for guiding resection of malignant gliomas. Invited talk presented at: 18th World Congress of Neurosurgery; 2023 Dec; Cape Town, South Africa.
- Marcu L. Interventional FLIM: past, present, and future. Invited talk presented at: SPIE Advanced Biophotonics Conference; 2023 Nov; Jeju, Korea.
- Islam MS. AI-enabled detector array for deeper vision and sensing beyond the limit. Invited talk presented at: SciX 2023; 2023 Oct; Sparks, NV.
- Marcu L. Label-free fluorescence lifetime techniques for image-guided interventions. Invited talk presented at: Advances in Optics for Biotechnology, Medicine and Surgery XVII; 2023 Oct; Tomar, Portugal.
- Marcu L. FLIM in Surgical Oncology. Invited talk presented at: SciX 2023; 2023 Oct; Sparks, NV.
- Marcu L. Fluorescence Lifetime Imaging in Surgical Oncology. Invited talk presented at: 29th Annual Cancer Research Symposium, UC Davis; 2023 Oct.
- Marcu L. Fluorescence Lifetime Imaging of Coronary Atherosclerosis. Invited talk presented at: CVRI Retreat and Heart Day, UC Davis; 2023 Oct.
- Li XD. Low-coherence Biophotonics for the Brain. Keynote speech presented at: Light Conference 2023; 2023 Aug; Changchun, China.
- Li XD. Probing the Brain Using Low-coherence Light: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Invited talk presented at: International Nano-Optoelectronics Workshop; 2023 Jul; Wuerzburg, Germany.
- Marcu L. FLIM related. Four invited lectures presented at: BIOPHOTONICS SUMMER SCHOOL 2023, 11th International Graduate Summer School; 2023 Jun; Island of Ven.
- Li XD. Shedding Low Coherence Light on the Brain: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Keynote speech presented at: BMES Mid-Atlantic Research Day; 2023 May; Baltimore, MD.
- Li XD. Shedding Low Coherence Light on the Brain: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Keynote speech presented at: CYTO 2023, International Society for Advancement of Cytometry; 2023 May; Montréal, Québec, Canada.
- Marcu L. Fluorescence lifetime and morphological imaging of coronary atherosclerosis. Invited lecture presented at: Image Guidance in PCI; 2023 Apr; Rotterdam, Netherlands.
- Li XD. 2P Fiberscopy Imaging of Neural Activities in Freely-Behaving Rodents and Beyond. Presented at: Optica Biophotonics Congress, Optics in the Life Sciences; 2023 Apr; Vancouver, BC, Canada.
- Marcu L. Label-free fluorescence lifetime imaging for intraoperative real-time guidance of neurological procedures. Invited talk presented at: 20th Annual Congress of the Society for Brain Imaging; 2023 Feb; Los Angeles, CA.
- Li XD. Mesoscopic and Microscopic Biophotonics Imaging of the Brain. Webinar presented at: Optica; 2023 Feb.
- Li XD. 2P Fiberscopy for Brain Imaging in Freely-behaving Rodents. Keynote speech presented at: SPIE Photonics West 2023; 2023 Jan.
- Srinivasan VJ. Multi-scale photonics for the central nervous system in health and disease. Invited talk presented at: UC Davis BME Seminar Series; 2023 Feb.
- Srinivasan VJ. Scalable Human Brain Imaging with Time-of-Flight Filtered Diffuse Optical Interferometry. Invited talk presented at: Georgia Tech Neuro Seminar Series; 2023 Mar; Atlanta, GA.
- Srinivasan VJ. Scalable Human Brain Imaging with Time-of-Flight Filtered Diffuse Optical Interferometry. Invited talk presented at: Optica Conference on Lasers and Electro-Optics; 2023 May; San Jose, CA.
- Srinivasan VJ. Coherence engineering of a human brain interferometer to quantitatively and specifically measure cerebral blood flow. Invited talk presented at: Optica Imaging Congress, Computational Optical Sensing and Imaging; 2023 Aug; Boston, MA.
- Srinivasan VJ. Diffuse optics meets photonics. Invited tutorial presented at: 2023 IEEE Photonics Conference; 2023 Nov; Orlando, FL.
- Srinivasan VJ. Interferometric diffuse optics: past, present, and future. Invited talk presented at: SPIE Advanced Biophotonics Conference; 2023 Nov; Jeju, Korea.
- Qi J. Total-body Dynamic PET Imaging and Beyond. Presented at: Department of Radiology, Weill Cornell Medicine, Cornell University; 2023 Apr 27; New York, NY.
- Qi J. Direct Estimation of Kinetic Parameters in PET. Presented at: Open Kinetic Modeling Initiative Webinar; 2023 Feb 27.
2022 Publications
Journal Papers & Peer Reviewed Proceedings
- Alfonso-Garcia A, Cevallos SA, Lee JY, Li C, Bec J, Bäumler AJ, et al. Assessment of Murine Colon Inflammation Using Intraluminal Fluorescence Lifetime Imaging. Molecules. 2022 Feb 15;27(4):1317. doi:10.3390/molecules27041317 PubMed PMID: 35209104. PMCID: PMC8875403
- Alfonso-García A, Zhou X, Bec J, Nobel Anbunesan S, Fereidouni F, Jin LW, et al. First in patient assessment of brain tumor infiltrative margins using simultaneous time-resolved measurements of 5-ALA-induced PpIX fluorescence and tissue autofluorescence. J Biomed Opt. 2022 Feb;27(2):020501. doi:10.1117/1.JBO.27.2.020501 PubMed PMID: 35112514. PMCID: PMC8809358
- Bartolo-Perez C, Ahamed A, Mayet AS, Rawat A, McPhillips L, Ghandiparsi S, et al. Engineering the gain and bandwidth in avalanche photodetectors. Opt Express. 2022 May 9;30(10):16873–82. doi:10.1364/OE.446507 PubMed PMID: 36221521. PMCID: PMC9363021
- Li C, Bec J, Zhou X, Marcu L. Dual-modality fluorescence lifetime imaging-optical coherence tomography intravascular catheter system with freeform catheter optics. J Biomed Opt. 2022 Jul 1;27(7):076005. doi:10.1117/1.JBO.27.7.076005 PubMed PMID: 35864574. PMCID: PMC9300477
- Weyers BW, Birkeland AC, Marsden MA, Tam A, Bec J, Frusciante RP, et al. Intraoperative delineation of p16+ oropharyngeal carcinoma of unknown primary origin with fluorescence lifetime imaging: Preliminary report. Head Neck. 2022 Aug 1;44(8):1765–76. doi:10.1002/hed.27078 PubMed PMID: 35511208. PMCID: PMC9979707
- Kholiqov O, Zhou W, Zhang T, Zhao M, Ghandiparsi S, Srinivasan VJ. Scanning interferometric near-infrared spectroscopy. Opt Lett. 2022 Jan 1;47(1):110–3. doi:10.1364/OL.443533. PubMed PMID: 34951892; PMCID: PMC9281567.
- Ayaz H, Baker WB, Blaney G, Boas DA, Bortfeld H, Brady K, et al. Optical imaging and spectroscopy for the study of the human brain: status report. Neurophotonics. 2022;9(Suppl 2):S24001. doi:10.1117/1.NPh.9.S2.S24001. PubMed PMID: 36052058; PMCID: PMC9424749.
- Pillar N, Ozcan A. Virtual tissue staining in pathology using machine learning. Expert Rev Mol Diagn. 2022 Nov;22(11):987–9. doi:10.1080/14737159.2022.2153040. PubMed PMID: 36440487
- Zhang Y, Huang L, Liu T, Cheng K, de Haan K, Li Y, et al. Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks. Intell Comput. 2022;2022:9818965. doi:10.34133/2022/9818965.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Label-Free Virtual HER2 Immunohistochemical Staining of Breast Tissue Using Deep Learning. BME Front. 2022;2022:9786242. doi:10.34133/2022/9786242. PubMed PMID: 37850170; PMCID: PMC10521710.
- Yang X, Bai B, Li Y, Zhang Y, Liu T, de Haan K, et al. Virtual stain transfer in histology via cascaded deep neural networks. ACS Photonics. 2022. doi:10.1021/acsphotonics.2c00932.
- Fujiwara T, Sakamoto N, Nonaka J, Ma KL. A Visual Analytics Approach for Hardware System Monitoring with Streaming Functional Data Analysis. IEEE Trans Vis Comput Graph. 2022 Jun;28(6):2338–49. doi:10.1109/TVCG.2022.3165348. PubMed PMID: 35394909.
- Bauer D, Wu Q, Ma KL. FoVolNet: Fast Volume Rendering using Foveated Deep Neural Networks. IEEE Trans Vis Comput Graph. 2023 Jan;29(1):515–25. doi:10.1109/TVCG.2022.3209498. PubMed PMID: 36155446; PMCID: PMC10984251.
Preprint Archives
N/A
Conference Abstracts/Presentations
- Zhao M, Zhou W, Aparanji S, GhandiParsi S, Srinivasan VJ. Parallel interferometric Diffusing Wave Spectroscopy (iDWS) with Time-of-Flight Discrimination. Biophotonics Congress: Biomedical Optics 2022. 2022 Apr 24; Fort Lauderdale, FL: Optica Publishing Group.
- Liu SJ, Ghiasi S, Yang W. Fiber-based frequency-modulated continuous-wave near-infrared spectroscopy for transabdominal fetal pulse oximetry. Proc SPIE. 2022.
- Yang X, Bai B, Li Y, Zhang Y, Liu T, de Haan K, et al. Virtual histological stain transformations through cascaded deep neural networks. Presented at: Optica/OSA Frontiers in Optics + Laser Science Conference; 2022 Oct 17–20; Rochester, NY.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep Learning Enables Noninvasive, Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy. Presented at: Biomedical Engineering Society Annual Meeting; 2022 Oct 12–15; San Antonio, TX.
- Bai B, Wang H, Li Y, de Haan K, Zhang Y, Li J, et al. Virtual Immunohistochemical Staining of Label-free Breast Tissue Using Deep Learning. Presented at: Biomedical Engineering Society Annual Meeting; 2022 Oct 12–15; San Antonio, TX.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep learning-enabled, non-invasive virtual histology of skin using reflectance confocal microscopy. Presented at: SPIE Optics and Photonics; 2022 Aug 21–25; San Diego, CA. Paper 12204-35.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Virtual immunohistochemical staining of unlabeled tissue using deep learning. Presented at: SPIE Optics and Photonics; 2022 Aug 21–25; San Diego, CA. Paper 12204-36.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Deep learning-enabled virtual immunohistochemical staining of label-free breast tissue sections. Presented at: 22nd Annual UC Systemwide Bioengineering Symposium; 2022 Aug 8–10; University of California, Santa Barbara, CA.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep learning-based non-invasive skin virtual histology using reflectance confocal microscopy. Presented at: 22nd Annual UC Systemwide Bioengineering Symposium; 2022 Aug 8–10; University of California, Santa Barbara, CA.
- Zhang Y, de Haan K, Li J, Rivenson Y, Ozcan A. Neural network-based multiplexed and microstructured virtual staining of unlabeled tissue. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 15–20; San Jose, CA.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 15–20; San Jose, CA.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Deep Learning-based Virtual Immunohistochemical HER2 staining of Label-Free Breast Tissue. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 5–10; San Jose, CA
- Ozcan A. Deep Learning-enabled Optics. Plenary presented at: SPIE Photonics West, BiOS Hot Topics Plenary Session; 2022 Jan 22–27; San Francisco, CA
Invited Talks
- Marcu L. Label-Free Fluorescence Lifetime Imaging: Applications in Surgical Oncology, Precision Surgery, Intraoperative Molecular Imaging. Invited talk presented at: UPenn Abramson Cancer Center; 2022 Nov 11.
- Marcu L. Fluorescence Lifetime Imaging in Surgical Oncology. Invited seminar presented at: Miami Global Tumor Symposium; 2022 Nov 2.
- Marcu L. FLIM in Surgical Oncology. Keynote talk presented at: Virtual BioPhotonics Conference; 2022 Oct 26.
- Marcu L. Bringing Malignancy to Light in the Operating Theater. Invited talk presented at: Gordon Research Conference on Optics and Photonics in Medicine and Biology; 2022 Jul; Bates College, Lewiston, ME.
- Marcu L. FLIM-Guided Robotic Surgery. Keynote talk presented at: Hamlyn Symposium in Medical Robotics; 2022 Jun; London, UK.
- Marcu L. Bringing Malignancy to Light in the Operating Theater. Plenary talk presented at: OPTICA Congress in Biophotonics; 2022 Apr 20–23; Florida.
- Marcu L. Fluorescence Lifetime Imaging in Medical Applications. Invited seminar presented at: University of Michigan-Dearborn; 2022 Apr 1.
- Srinivasan VJ. Invited talk presented at: IEEE Indian Institute of Science Sensors and Nanotechnology Joint Council Chapter in association with IEEE IISc Student Branch; 2022 May.
- Qi J. Total-Body PET Imaging. Presented at: Department of Nuclear Medicine, Bern University Hospital, University of Bern; 2022 Nov 14; Bern, Switzerland.
All Publications (2022-2026)
Journal Papers & Peer Reviewed Proceedings
- Z. Zhang, S. Liu, M. Zhao, W. Zhou, A. Fu, S. Ghiasi, V. J. Srinivasan, and W. Yang, "Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.4.
- R. R. Joarder, W. Yang, V. J. Srinivasan, and S. Ghiasi, "DIGSS: Depth Isolation via Gating and Signal Separation — A Simulation Study of Pulsatile Time-Domain NIRS," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper TS4D.3.
- Adams AC, Alfonso Garcia A, Noble Anbunesan S, Kraft L, Bec J, Lee HS, et al. Fluorescence lifetime imaging of 5-ALA-induced PpIX and autofluorescence for detecting infiltrating glioblastoma margins in patients. Biomed Opt Express. 2026 Mar 1;17(3):1267–78. doi:10.1364/BOE.581578 PubMed PMID: 41970566. PMCID: PMC13064626
- Ahamed A, Myat H, Rawat A, McPhillips LN, Islam MS. AI-augmented photon-trapping spectrometer-on-a-chip on silicon platform with extended near-infrared sensitivity. Advanced Photonics. 2026 Jan 19;8(01). doi:10.1117/1.AP.8.1.016008
- Bec J, Zhou X, Tipirneni Y, Chen S, Qi J, Iczkowski KA, et al. Label-free fluorescence lifetime imaging for rapid discrimination of high-grade prostate cancer in fresh biopsy cores: a feasibility study. J Biomed Opt. 2026 Mar 2;31(3):036001. doi:10.1117/1.JBO.31.3.036001 PubMed PMID: 41778026. PMCID: PMC12950611
- Goldschmidt S, Marcu L, Ehrlich K, Hassan MA, Rivas I, Birkeland A, et al. Label-free fluorescence lifetime imaging can distinguish cancer from healthy tissue in spontaneously occurring canine oral tumors. Sci Rep. 2026 Jan 23;16(1):6077. doi:10.1038/s41598-026-37001-3 PubMed PMID: 41578004. PMCID: PMC12902045
- Liu X, Adams AC, Zhou X, Bec J, Marcu L. Fluorescence properties of collagen types I-V: a comprehensive study of spectral and lifetime characteristics. J Biomed Opt. 2026 Jun;31(6):065001. doi: 10.1117/1.JBO.31.6.065001. Epub 2026 Jun 27. PMID: 42367579; PMCID: PMC13309843.
- Zhou X, Marcu L.Intravascular Fluorescence Lifetime Imaging: from Bench to Catheterization Lab. Curr Treat Options Cardio Med 28, 24 (2026). https://doi.org/10.1007/s11936-026-01155-0
- Fereidouni F, Ju W, Rezapourdamanab S, Sayrafi D, Hassan MA, Weyers B, Zhou X, Bec J, Gui D, Birkeland A, Marcu L. Effects of surgical resection on tissue autofluorescence lifetime signatures in head and neck cancer: implications for intraoperative tumor margin assessment. J Biomed Opt. 2026 Sep;31(9):096002. doi: 10.1117/1.JBO.31.9.096002. Epub 2026 Sep 4. PubMed PMID: 42699387; PubMed Central PMCID: PMC13544624.
- Zhou L, Yuan N, Hassan MA, Kraft L, Ehrlich K, Weyers BW, Ivanovic V, Raslan OAA, Gui D, Abouyared M, Bewley AF, Birkeland AC, Farwell DG, Marcu L, Qi J. Multimodal Fusion of Intraoperative FLIm and Preoperative PET/CT for Patient-Level Prediction of Lymph Node Metastasis in Head and Neck Cancer. Cancers (Basel). 2026 Jul 4;18(13). doi: 10.3390/cancers181321
- Alfonso-Garcia A, Bec J, Hassan MA, Noble Anbunesan S, Kraft L, Bobinski M, et al. Label-free fluorescence lifetime imaging for real-time guidance of stereotactic biopsy: A feasibility study in brain cancer patients. Neurooncol Adv. 2025;7(1):vdaf172. doi:10.1093/noajnl/vdaf172 PubMed PMID: 41104039. PMCID: PMC12527272
- Baldini F, Dholakia K, French P, Guntinas-Lichius O, Kohler A, Mäntele W, et al. Shining a Light on the Future of Biophotonics. J Biophotonics. 2025 Jul;18(7):e202500148. doi:10.1002/jbio.202500148 PubMed PMID: 40364668. PMCID: PMC12245495
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Preprint Archives
- Nobel Anbunesan S, Hassan MA, Qi J, Kraft L, Lee HS, Bloch O, et al. A Data-Centric Framework for Intraoperative Fluorescence Lifetime Imaging for Glioma Surgical Guidance. ArXiv. 2026 Apr 28. Available from: http://arxiv.org/abs/2604.26147
- Xu S, Liu J, Wang SH, Broecker S, Huang Y, Wang B, and Strohmer T. CyclOT: Learning Quadratic Optimal Transport Maps via Synchronized Forward–Backward Interpolants, ArXiv. 2026 Sept 12. Available from: https://arxiv.org/html/2609.13892v1
- Broecker S, Adams JY, Kumar G, Callcut RA, Ni Y, Strohmer T. Multimodal Deep Learning for ARDS Detection. medRxiv. 2026 Aug 12. Available from: https://www.medrxiv.org/content/10.1101/2025.08.08.25333333v1
- Liu R, Ranganathan V, Dahlbom D, Xu S, Zhang T, Ni Y, Pajerowski DM, Granroth G, Strohmer T, Stone MB, May AF. Observation geometry for uncertainty-aware Hamiltonian inference and experimental design in quantum magnets. ArXiv. 2026 Aug 11. Available from: https://arxiv.org/html/2608.10350v1
- Xu S, Strohmer T. Machine unlearning via information theoretic regularization. ArXiv 2026 Jul 6. Available from: https://arxiv.org/abs/2502.05684
- Xu S, Ni Y, Broecker S, Strohmer T. Forgetting-MarI: LLM unlearning via marginal information regularization. ArXiv. 2026 Jan 17. Available from: https://arxiv.org/abs/2511.11914
- Broecker S, del Rosario M, Selitser B, Strohmer T. The “I Don’t Know” Filter: Enhancing Agentic Reliability in Function Calling. ArXiv. 2026 Jul 4. Available from: https://arxiv.org/abs/2607.04034
- Hassan MA, Kraft L, Azam MA, Bec J, Hadfield KT, Qi J, et al. Enhancing Label-Free Fluorescence Lifetime Imaging for Intraoperative Tumor Margin Delineation in Head and Neck Cancer using Data-Centric AI. Res Sq. 2025 May 23;rs.3.rs-6673642. doi:10.21203/rs.3.rs-6673642/v1 PubMed PMID: 40470246. PMCID: PMC12136734
- Saffarpour M, Vali K, Qian W, Kasap B, Hedriana HL, Ghiasi S. Deep Harmonic Finesse: Signal Separation in Wearable Systems with Limited Data. Proc Des Autom Conf. 2024 Jul 1. doi:10.1145/3649329.3657339. Available from: https://arxiv.org/abs/2407.01840
- Yang X, Aydin M, Lu Y, Selcuk SY, Bai B, Zhang Y, et al. Autonomous labeling of surgical resection margins using a foundation model. ArXiv. 2025 Nov 27. PubMed PMID: 41356060. Available from: http://arxiv.org/abs/2511.22131
- He Y, Strohmer T, Vershynin R, Zhu Y. Differentially Private Low-dimensional Synthetic Data from High-dimensional Datasets. ArXiv. 2024 Dec 11. Available from: http://arxiv.org/abs/2305.17148
- Xu S, Strohmer T. WHOMP: Optimizing Randomized Controlled Trials via Wasserstein Homogeneity. ArXiv. 2024 Oct 3. Available from: http://arxiv.org/abs/2409.18504
- Xu S, Strohmer T. On the (In)Compatibility between Group Fairness and Individual Fairness. ArXiv. 2024 Jan 13. Available from: http://arxiv.org/abs/2401.07174
- Feng X, Strohmer T. Improving Autoencoder Image Interpolation via Dynamic Optimal Transport. ArXiv. 2024 Apr 13. Available from: http://arxiv.org/abs/2404.08900
- Kumar G, Strohmer T, Vershynin R. An Algorithm for Streaming Differentially Private Data. ArXiv. 2024 Jan 31. Available from: http://arxiv.org/abs/2401.14577
Conference Abstracts/Presentations
- Z. Zhang, S. Liu, M. Zhao, W. Zhou, A. Fu, S. Ghiasi, V. J. Srinivasan, and W. Yang, "Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment," in Optica Biophotonics Congress 2026, Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.4.
- Ahamed A, Rawat A, Marcu L, Islam MS. Photon-trapping surface structures in ultrafast photodetectors: overcoming hardware limits with AI-driven computational imaging. Proc SPIE. 2026 Mar;13899:1389902.
- McPhillips LN, Rawat A, Ponizovskaya-Devine E, Islam MS. Boosting pixel efficiency through metasurfaces in deadspace regions. Proc SPIE. 2026 Mar;13908:67–73.
- Ahamed A, Myat H, Islam MS. AI-assisted hyperspectral imaging for narrow-band lasers using photon-trapping silicon photodiodes. Proc SPIE. 2026 Mar;13902:69–75.
- Islam MS. Photon-trapping single-photon detectors: enabling precision sensing beyond conventional limits. Invited paper presented at: SPIE Photonics West; 2026 Jan 22; San Francisco, CA. Paper 13920-136.
- Adams A. Fluorescence properties of collagen types I-V: a comprehensive spectral and lifetime analysis. Presented at: SPIE Photonics West Conference; 2026 Jan 21; San Francisco, CA. Conference 13855.
- Ahamed A, Myat H, Islam MS. AI-assisted hyperspectral imaging for narrow-band lasers using photon-trapping silicon photodiodes. Presented at: SPIE Photonics West; 2026 Jan 20; San Francisco, CA. Paper 13902-23.
- Ahamed A, Islam MS. Quantum true random number generator based on photon-trapping avalanche photodiodes. Presented at: SPIE Photonics West; 2026 Jan 18; San Francisco, CA. Paper 13919-12.
- Islam MS. Photon-trapping surface structures in ultrafast photodetectors: overcoming hardware limits with AI-driven computational imaging. Invited paper presented at: SPIE Photonics West; 2026 Jan 18; San Francisco, CA. Paper 13899-2.
- Kristen C. Dual-modality fluorescence lifetime imaging and polarization sensitive optical coherence tomography system for optical biopsy in brain. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13859.
- Ouyang X. Identification and Characterization of Biochemical and Morphological Markers of Atherosclerotic Plaque Progression Using Integrated FLIm-PSOCT Imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13826.
- Zhou X. Label-free characterization of human coronary arteries plaques via high-resolution laser scanning multispectral fluorescence lifetime imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 18; San Francisco, CA. Conference 13826.
- Adams A. Fluorescence lifetime sensitivity to immune infiltration during glioma resection. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13838.
- Adams A. Real-time spatial augmentation of fluorescence lifetime imaging on preoperative MRI for brain tumor resection guidance. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13838.
- Bec J. Rapid discrimination of high-grade prostate cancer using label-free fluorescence lifetime measurement in biopsy specimens. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13824.
- Hassan MA. EdgeWise: Real-time margin mapping in head-and-neck cancer with label-free fluorescence-lifetime imaging. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13825.
- Thrapp A. Combined fluorescence lifetime imaging and interferometric near infrared spectroscopy for burn assessment. Presented at: SPIE Photonics West Conference; 2026 Jan 17; San Francisco, CA. Conference 13841.
- Zhou X, et al. Combined multispectral FLIm/polarization-sensitive OCT catheter system for detection of macrophage foam cells in human atherosclerotic lesions. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Sun P, et al. Dynamic real-world scaling for enhanced PS-FLIm data visualization in TORS. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Hassan M, et al. Data-centric learning framework for real-time surgical guidance using fiber-based FLIm. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Liu X, et al. Multispectral pulse-sampling fluorescence lifetime imager for high-speed large-scale tissue imaging. Presented at: SPIE Photonics West BiOS 2025; 2025 Jan; San Francisco, CA.
- Adams A, Alfonso-Garcia A, Anbunesan SN, Bec J, Lee HS, Bloch O, et al. Enhanced In Vivo Detection of Glioblastoma’s Infiltrative Edge Using FLIm. Optica Biophotonics Congress 2025, Technical Digest Series. 2025; paper TW2F.5.
- Kekula Z, Rawat A, Islam MS. Sensitivity analysis of Si-avalanche photodiode for noise performance assessment. 2024 IEEE Nanotechnology Materials and Devices Conference. 2024 Oct;114–116.
- Alfonso-Garcia A, Kraft L, Zhou X, Bec J, Marcu L, Wei D, et al. Colorectal Polyp Assessment with Label-Free Fluorescence Lifetime Imaging. Optica Biophotonics Congress: Biomedical Optics 2024, Technical Digest Series. 2024; paper TM3B.2. doi:10.1364/TRANSLATIONAL.2024.TM3B.2.
- Ehrlich K, Hadfield KT, Hassan MA, Kraft L, Qi J, Gui D, et al. The Effect of Risk Factors on the Fluorescence Lifetime in Oropharyngeal Cancer. Optica Biophotonics Congress: Biomedical Optics 2024, Technical Digest Series. 2024; paper TTu3B.2. doi:10.1364/TRANSLATIONAL.2024.TTu3B.2.
- Bec J, et al. Demonstration of a combined multispectral FLIm/polarization-sensitive OCT catheter system for biochemical/structural evaluation of atherosclerosis lesions. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Bai Y, Rawat A, McPhillips LN, Islam MS. P-on-N versus N-on-P Silicon-Avalanche Photodiode Selection for Visible and Near Infrared Wavelength Applications. 2024 Device Research Conference. 2024; 1–2. doi:10.1109/DRC61706.2024.10605335.
- Rawat A, Islam SM. High-speed PiN photodiode design space exploration to break the speed-efficiency trade-off. Proc SPIE. 2024; 12880:194–200. doi:10.1117/12.3003413.
- Islam MS, Ahamed A, McPhillips LN, Rawat A. Precision photon manipulation in photodetectors for AI-driven ultrafast sensing and imaging. Proc SPIE. 2024; 12895: PC128950B. doi:10.1117/12.3007784.
- Alfonso-Garcia A, Lee JY, Condon A, Zhou X, Bec J, Baumler AJ, et al. Assessing in vivo label-free fluorescence lifetime imaging sensitivity to low-grade colon inflammation. Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases. 2024. doi:10.1117/12.3002008. Presented at: SPIE Photonics West 2024; 2024 Jan
- Ehrlich K, Hadfield KT, Kraft L, Hassan MA, Weyers BW, Zhou X, et al. Investigating fluorescence lifetime signatures for normal tissue adjacent to cancer in oropharyngeal squamous cell carcinomas. Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology. 2024. doi:10.1117/12.3003488. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Noble Anbunesan S, Alfonso-Garcia A, Bec J, Hassan M, Kraft L, Bobinski M, et al. Optical biopsy of brain tumors using fluorescence lifetime imaging. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems. 2024; PC1283101. doi:10.1117/12.3001898. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Hassan MA, Noble Anbunesan S, Alfonso-Garcia A, Bobinski M, Lee HS, Jin LW, et al. Detecting infiltrative edges of brain tumors using label-free intraoperative FLIm. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems. 2024; PC1283102. doi:10.1117/12.3003609. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Hassan MA, Weyers BW, Bec J, Qi J, Gui D, Bewley AF, et al. Mesoscopic FLIm for detection of residual cancer in transoral robotic surgery. Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology. 2024. doi:10.1117/12.2545150.6138709753001. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Ahamed A, Rawat A, McPhillips LN, Marcu L, Islam MS. On-chip hyperspectral detectors for fluorescence lifetime imaging. Proc SPIE. 2024; 12853:1285304. doi:10.1117/12.3002476. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Rawat A, Islam SM. Direction of arrival sensing enabled by introducing asymmetric surface structures in photodetectors. Proc SPIE. 2024; 12880:201–207. doi:10.1117/12.3003432.
- Islam MS, Rawat A, Tsubokawa M. Meta surface-enabled circular light propagation for ultra-fast and efficient photodetection. Proc SPIE. 2024; 13114:36–42. doi:10.1117/12.3030510.
- McPhillips LN, Rawat A, Ahamed A, Islam MS. DC linearity and absorption efficiency enhancement by introducing photon-trapping microstructures into avalanche photodetectors. Proc SPIE. 2024; 12895:90–96. doi:10.1117/12.3003649.
- Ahamed A, Rawat A, McPhillips LN, Wang SY, Islam MS. Scalable photodetector design with sub-picosecond response time. Proc SPIE. 2024; 12895:97–104. doi:10.1117/12.3002441. Presented at: SPIE Photonics West 2024; 2024 Jan.
- Kobayashi NP, Talin AA, Davydov AV, Islam MS, editors. Low-Dimensional Materials and Devices 2024. Proc SPIE. 2024; 13114:1311401-1. doi:10.1093/oso/9780198517818.003.0004.
- Knapp T, Duan S, Alfonso-Garcia A, Merchant JL, Sawyer TW. Validation of label-free optical imaging markers of pancreatic cancer using spatial transcriptomics. Label-free Biomedical Imaging and Sensing. 2024; 12854:29–42. doi:10.1117/12.2691452.84be641d-5410-ee11-a99a-b38e0bc17c27.
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: Women in Photonics 2023; 2023 Nov.
- Hassan MA, et al. FLIm-Based in Vivo Classification of Residual Cancer in the Surgical Cavity During Transoral Robotic Surgery. Poster presented at: Cancer Center Symposium 2023; 2023 Oct.
- Hassan MA, et al. FLIm-Based in Vivo Classification of Residual Cancer in the Surgical Cavity During Transoral Robotic Surgery. Presented at: International Conference on Medical Image Computing and Computer-Assisted Intervention; 2023 Oct.
- Condon A, Alfonso-Garcia A, et al. Evaluation of the Sensitivity of Fluorescence Lifetime Imaging to Low-Grade Inflammation in an Ex Vivo Murine Model. Poster and oral presentation at: Annual UC Systemwide Bioengineering Symposium; 2023 Jun.
- Alfonso-Garcia A, et al. iFLIM: optical biopsy for colorectal cancer. Poster presented at: Cancer Center Symposium 2023; 2023 May.
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: UC Davis BMEGG Symposium; 2023 May.
- Noble Anbunesan S, et al. Intraoperative detection of glioma infiltrating edges: comparative analysis between interventional fluorescence lifetime imaging and preoperative MRI-based neuronavigation. Presented at: Optica Biophotonics Congress 2023; 2023 Apr.
- Hassan MA, et al. Anatomy-specific classification models using FLIm for head and neck cancer surgical guidance. Presented at: SPIE Photonics West BiOS 2023; 2023 Mar.
- Zhou X, et al. Photon economy of pulse-sampling vs TCSPC fluorescence lifetime imaging. Presented at: SPIE Photonics West 2023; 2023 Mar.
- Noble SA, et al. Intraoperative detection of IDH-mutant glioma using fluorescence lifetime imaging. Presented at: SPIE Photonics West 2023; 2023 Mar.
- Zhang Z, Liu SJ, Zhao M, Zhou W, Fu A, Ghiasi S, et al. Dual-wavelength interferometric diffusing wave spectroscopy with a time-of-flight filter (TOF-iDWS) for tissue oxygenation and perfusion assessment. Optica Biophotonics Congress. Accepted 2026.
- Zhao M, Srinivasan VJ. Improving the time-of-flight filter in highly parallel interferometric diffusing wave spectroscopy (iDWS). Clinical and Translational Neurophotonics 2026. Proc SPIE. 2026 Mar 5; 13834:138340F. doi:10.1117/12.3081261.
- Thrapp A, Samanta R, Liu X, et al. Combined fluorescence lifetime imaging and speckle modulation interferometric near infrared spectroscopy for burn assessment. Multimodal Biomedical Imaging XXI. Proc SPIE. 2026 Mar 6; PC13841:PC1384108. doi:10.1117/12.3083349.
- Joarder R, Yang W, Srinivasan VJ, Ghiasi S. DIGSS: Depth Isolation via Gating and Signal Separation — a Simulation Study of Pulsatile Time-Domain NIRS. Biophotonics Congress. 2026; paper TS4D.3.
- Samanta R, Zhou W, Srinivasan VJ. Free-Space Interferometric Diffusing Wave Spectroscopy With an 8-bit Camera. Optica Biophotonics Congress: Biomedical Optics 2026 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series (Optica Publishing Group, 2026), paper OS1D.3
- Vali K, Kasap B, Vafi A, Ghiasi S. JOIN: Optimized Light Source Activation for Deep Tissue Optical Sensing. Presented at: IEEE/ACM International Conference on Cyber-Physical Systems; 2025.
- Fowler R, Kasap B, Joarder R, Ghiasi S. Non-invasive Fetal Blood pH Estimation for Enhanced Intrapartum Monitoring using Near-Infrared Spectroscopy. Presented at: Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 2025.
- Lihe L, Qian W, Kasap B, Ghiasi S. PSAFE: Extraction of Faint Fetal PPG from Non-Invasively Acquired Mixed PPG Signals. Presented at: IEEE Body Sensor Networks; 2025.
- Qian W, Joarder R, Fowler R, Kasap B, Saffarpour M, Ghiasi S. Blind Source Separation for Fetal PPG with Rate-Based Proxy Supervision. Presented at: NeurIPS Workshop on Learning from Time Series for Health; 2025.
- Aparanji S, Zhao M, Nadig A, Estrada HG, Hamilton D, Srinivasan VJ. Time-of-flight filtered long wavelength interferometric diffusing wave spectroscopy. Clinical and Translational Neurophotonics 2025. Proc SPIE. 2025; PC133020B.
- Mazumder D, Aparanji S, Kholiqov O, Hamilton D, Estrada HG, Samanta R, et al. Interferometric near-infrared spectroscopy (iNIRS) at 1060 nm. Clinical and Translational Neurophotonics 2025. Proc SPIE. 2025; PC133020D.
- Samanta R, Mazumder D, Kholiqov O, Srinivasan VJ. Dynamic speckle-modulated interferometric near-infrared spectroscopy of non-ergodic samples. Optics and the Brain. 2025; paper BW1B.2. Optica Publishing Group.
- Srinivasan VJ. High-throughput human cerebral blood flow monitoring with interferometric diffuse optics. High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond X. Proc SPIE. 2025; PC133300E.
- Srinivasan VJ. Interferometric diffuse optics: recent advances and future outlook. Computational Optical Imaging and Artificial Intelligence in Biomedical Sciences II. Proc SPIE. 2025; PC133330H.
- Meng R, Gupta AK, Srinivasan VJ. Optoretinography with visible light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2025; 66:4794.
- Meng R, Gupta AK, Srinivasan VJ. Quantifying Bruch’s membrane thickness in aging with visible light optical coherence tomography. Ophthalmic Technologies XXXV. Proc SPIE. 2025;PC133000C.
- Srinivasan V, Gupta A. Anatomically informed imaging and quantification of macular pigments in the living human eye with visible light Optical Coherence Tomography. J Alzheimers Dis. 2025.
- Chauhan P, Kho A, Srinivasan V. Inner nuclear layer sublamination in the mouse with visible light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2025;66:1501.
- Gupta AK, Meng R, Srinivasan V. A clinical visible light OCT system with superluminescent diodes (SLDs). Invest Ophthalmol Vis Sci. 2025; 66:1500.
- Ghiasi S. Deep Quasi-Periodic Priors: Signal Separation in Wearable Systems with Limited Data. Presented at: IEEE/ACM Design Automation and Test in Europe; 2024 Mar.
- Zhou W, Zhao M, Srinivasan VJ. A generalized form of the modified Siegert relationship. Presented at: Dynamics and Fluctuations in Biomedical Photonics XXI; 2024. Proc SPIE.
- Zhao M, Aparanji S, Srinivasan VJ. Recovering tissue properties with a time-of-flight informed interferometric diffusing wave spectroscopy (iDWS) system. Proc SPIE. 2024.
- Majeski JB, Chong SH, Ramachandran NR, Abramson K, Aparanji S, Zhao M, et al. Comparison of diffuse correlation spectroscopy, speckle contrast optical spectroscopy, and interferometric diffusing wave spectroscopy for blood flow monitoring. Proc SPIE. 2024.
- Joarder R, Yang W, Srinivasan VJ, Ghiasi S. Inverse Modeling Approach for Fetal Oxygen Saturation Estimation with Spatial Intensity. Optica Biophotonics Congress: Biomedical Optics 2024. 2024; paper JS4A.1.
- Majeski J, Forti R, Chong S, Ramachandran N, Abramson K, Aparanji S, et al. A Comparative Study of Blood Flow Monitoring Using Interferometric Diffusing Wave Spectroscopy, Speckle Contrast Optical Spectroscopy, and Diffuse Correlation Spectroscopy. Optical Tomography and Spectroscopy. 2024; Optica Publishing Group.
- Forti RM, Majeski J, Mason M, Weeks M, Ramachandran N, Abramson K, et al. Performance assessment methodologies for diffuse optical flow technologies. Optical Tomography and Spectroscopy. 2024; Optica Publishing Group.
- Kasap B, Vali K, Qian W, Mo L, Chithiwala ZH, Hedriana HL, et al. Use of A Novel Transabdominal Fetal Pulse Oximeter (TFO) In Human Pregnancy: A Proof-of-Concept. Am J Obstet Gynecol. 2023 Jan 1; 228(1):S100. doi:10.1016/j.ajog.2022.11.211
- Qian W, Vali K, Kasap B, Pivetti CD, Theodorou CM, Kulubya ES, et al. Continuous Transabdominal Fetal Pulse Oximetry (TFO) in Pregnant Ewe Models under Induced Fetal Hypoxia. Am J Obstet Gynecol. 2023; 228(1):S242–S3. doi:10.1016/j.ajog.2022.11.441.
- Aparanji S, Zhao M, Srinivasan VJ. Interferometric diffusing wave spectroscopy with an optical time-of-flight switch. Presented at: Dynamics and Fluctuations in Biomedical Photonics XX; 2023. Proc SPIE.
- Liu S, Lee Y, Pivetti C, Kulubya E, Wang A, Farmer D, et al. Transabdominal fetal signals measurement using fiber-based frequency-modulated continuous-wave near-infrared spectroscopy in a fetal lamb model. Biophotonics Congress: Optics in the Life Sciences 2023, Technical Digest Series. 2023; paper DW4A.6.
- Mazumder D, Kholiqov O, Srinivasan VJ. Dual-wavelength interferometric near-infrared spectroscopy (iNIRS). Bio-Optics: Design and Application. 2023; Optica Publishing Group.
- Zhao M, Zhou W, Aparanji S, Mazumder D, Srinivasan VJ. Interferometric diffusing wave spectroscopy imaging with an electronically variable time-of-flight filter. Proc SPIE. 2023.
- Ghiasi S. BASS: Safe Deep Tissue Optical Sensing for Wearable Embedded Systems. Presented at: IEEE/ACM International Conference on Hardware/Software Codesign and System Synthesis; Sept 2023.
- Kasap B. Robust Fetal Heart Rate Tracking through Fetal Electrocardiography (ECG) and Photoplethysmography (PPG) Fusion. Presented at: 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 2023.
- Joarder R. RT-TRAQ: An algorithm for real-time tracking of faint quasi-periodic signals in noisy time series. Presented at: IEEE/ACM International Conference on Connected Health: Applications, Systems and Engineering Technologies; 2023.
- Zhao M, Zhou W, Aparanji S, GhandiParsi S, Srinivasan VJ. Parallel interferometric Diffusing Wave Spectroscopy (iDWS) with Time-of-Flight Discrimination. Biophotonics Congress: Biomedical Optics 2022. 2022 Apr 24; Fort Lauderdale, FL: Optica Publishing Group.
- Liu SJ, Ghiasi S, Yang W. Fiber-based frequency-modulated continuous-wave near-infrared spectroscopy for transabdominal fetal pulse oximetry. Proc SPIE. 2022.
- Wang Z, Xuan X, Ma KL. Interactive Surgical Visualization with Real-Time Endoscopic Scene Reconstruction and Functional Imaging Overlay. Presented at: 2026 IEEE 23rd International Symposium on Biomedical Imaging; 2026.
- Xuan X, Deng Z, Ma KL. ReME: A Data-Centric Framework for Training-Free Open-Vocabulary Segmentation. Presented at: IEEE/CVF International Conference on Computer Vision; 2025.
- Malik D, Xuan X, Ma KL. Towards Interactive 3D Surgical Scene Reconstruction: an Incremental Training and Monitoring Framework. Presented at: 2025 IEEE 22nd International Symposium on Biomedical Imaging; 2025 Apr 14–17; Houston, TX.
- Wang Z, Xuan X, Ma KL. Interactive Surgical Visualization with Real-Time Endoscopic Scene Reconstruction and Functional Imaging Overlay. Presented at: 2025 IEEE 23rd International Symposium on Biomedical Imaging; 2025 Apr 8–11; Houston, TX.
- Zhou L, Yuan N, Qi J. NCF: Neural Correspondence Field for Medical Image Registration. Presented at: SPIE Medical Imaging Symposium, Imaging Processing Conference; 2025 Feb; San Diego, CA.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep Learning Enables Virtual Histological Staining of Label-free Autopsy Tissue Sections. Presented at: Biomedical Engineering Society Annual Meeting; 2024 Oct 23–26; Baltimore, MD.
- Yang X, Selcuk SY, Bai B, Zhang Y, Li Y, Aydin M, et al. Deep learning-based HER2 Scoring of Breast Cancer Images Using Pyramid Sampling. Presented at: Biomedical Engineering Society Annual Meeting; 2024 Oct 23–26; Baltimore, MD.
- Xu S. Fair Data Representation for Machine Learning at the Pareto Frontier. Presented at: BIRS/CMO Workshop on Computational Harmonic Analysis in Data Science and Machine Learning; 2024 Sep; Oaxaca, Mexico.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep learning-enabled virtual staining of label-free autopsy tissue sections. Presented at: SPIE Optics and Photonics; 2024 Aug 18–22; San Diego, CA. Paper 13118-38.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Classification of HER2 score in breast cancer images using deep learning and pyramid sampling. Presented at: SPIE Optics and Photonics; 2024 Aug 18–22; San Diego, CA. Paper 13118-17.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Deep learning-enabled virtual staining of unlabeled autopsy tissue sections. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Yang X, Bai B, Zhang Y, Aydin M, Li Y, Selcuk SY, et al. Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling. Presented at: 24th Annual UC Systemwide Bioengineering Symposium; 2024 Jun 24–25; University of California, San Diego, CA.
- Broecker S. Multimodal data analysis, with applications to ARDS diagnosis. Presented at: International Pediatric and Lifespan Data Science Conference; 2024 May; Anaheim, CA.
- Li Y, Pillar N, Li J, Liu T, Wu D, Sun S, et al. Virtual histological staining of label-free autopsy tissue sections via deep learning. Presented at: Optica Conference on Lasers and Electro-Optics; 2024 May 5–10; Charlotte, NC.
- Selcuk SY, Yang X, Bai B, Zhang Y, Li Y, Aydin M, et al. Deep Learning-Enabled Classification of HER2 Score in Breast Cancer Using Pyramid Sampling. Presented at: Optica Conference on Lasers and Electro-Optics; 2024 May 5–10; Charlotte, NC.
- Zhang Y, Huang L, Liu T, Cheng K, de Haan K, Li Y, et al. Neural network-based virtual staining of defocused autofluorescence images of label-free tissue. Presented at: Conference on Lasers and Electro-Optics; 2023;1–2.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Darrow MA, et al. Virtual HER2 staining of label-free breast tissue using autofluorescence imaging and deep learning. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI. Proc SPIE. 2023;PC12368:PC123680J. doi:10.1117/12.2648173.
- Ozcan A. Virtual staining of label-free tissue using deep learning. Presented at: Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI; 2023;PC1262207.
- Ozcan A. Overview on deep-learning-enabled computational microscopy and diffractive imaging. Presented at: Quantitative Phase Imaging IX; 2023. Proc SPIE. 2023;PC12389:PC1238901. doi:10.1117/12.2674088.
- Yang X, Bai B, Li Y, Zhang Y, Liu T, de Haan K, et al. Virtual stain-to-stain transformations via cascaded deep neural networks. Multimodal Biomedical Imaging XVIII. Proc SPIE. 2023;PC12371:PC123710C. doi:10.1117/12.2648101.
- Yang X, Bai B, Li Y, Zhang Y, Liu T, de Haan K, et al. Virtual histological stain transformations through cascaded deep neural networks. Presented at: Optica/OSA Frontiers in Optics + Laser Science Conference; 2022 Oct 17–20; Rochester, NY.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep Learning Enables Noninvasive, Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy. Presented at: Biomedical Engineering Society Annual Meeting; 2022 Oct 12–15; San Antonio, TX.
- Bai B, Wang H, Li Y, de Haan K, Zhang Y, Li J, et al. Virtual Immunohistochemical Staining of Label-free Breast Tissue Using Deep Learning. Presented at: Biomedical Engineering Society Annual Meeting; 2022 Oct 12–15; San Antonio, TX.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep learning-enabled, non-invasive virtual histology of skin using reflectance confocal microscopy. Presented at: SPIE Optics and Photonics; 2022 Aug 21–25; San Diego, CA. Paper 12204-35.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Virtual immunohistochemical staining of unlabeled tissue using deep learning. Presented at: SPIE Optics and Photonics; 2022 Aug 21–25; San Diego, CA. Paper 12204-36.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Deep learning-enabled virtual immunohistochemical staining of label-free breast tissue sections. Presented at: 22nd Annual UC Systemwide Bioengineering Symposium; 2022 Aug 8–10; University of California, Santa Barbara, CA.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Deep learning-based non-invasive skin virtual histology using reflectance confocal microscopy. Presented at: 22nd Annual UC Systemwide Bioengineering Symposium; 2022 Aug 8–10; University of California, Santa Barbara, CA.
- Zhang Y, de Haan K, Li J, Rivenson Y, Ozcan A. Neural network-based multiplexed and microstructured virtual staining of unlabeled tissue. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 15–20; San Jose, CA.
- Li J, Garfinkel J, Zhang X, Wu D, Zhang Y, de Haan K, et al. Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 15–20; San Jose, CA.
- Bai B, Wang H, Li Y, de Haan K, Colonnese F, Wan Y, et al. Deep Learning-based Virtual Immunohistochemical HER2 staining of Label-Free Breast Tissue. Presented at: OSA/Optica Conference on Lasers and Electro-Optics; 2022 May 5–10; San Jose, CA
- Ozcan A. Deep Learning-enabled Optics. Plenary presented at: SPIE Photonics West, BiOS Hot Topics Plenary Session; 2022 Jan 22–27; San Francisco, CA
Invited Talks
- Marcu L. Interventional FLIM: What it takes to move from bench to operating theater. Presented at: BIOS 2026, SPIE Photonics West; 2026 Jan; San Francisco, CA.
- A. Ozcan, "Virtual staining of label-free tissue," Annual Rice University Center for Nanoscale Imaging Sciences Conference, Rice University, November 18, 2025, Houston, TX, USA (Keynote Talk)
- Srinivasan VJ. Interferometric diffuse optics: recent advances and future outlook. Plenary/Hot Topics talk presented at: SPIE Photonics West; 2025 Jan 25; San Francisco, CA.
- Srinivasan VJ. High-throughput human cerebral blood flow monitoring with interferometric diffuse optics (Invited Paper). Invited talk presented at: SPIE Photonics West; 2025 Jan 25; San Francisco, CA.
- Srinivasan VJ. Invited talk presented at: Oculomics Session; 2025 May; Salt Lake City, UT.
- Srinivasan VJ. Anatomically informed imaging and quantification of macular pigments in the living human eye with visible light optical coherence tomography. Invited talk presented at: Brain and Ocular Nutrition (BON) Conference; 2025 Jun 19; Beverly, MA.
- Marcu L. Fluorescence Lifetime Imaging in Clinical Interventions. Invited seminar presented at: Wyant College of Optical Sciences; 2025 Dec 4; Tucson, AZ.
- Marcu L. Advancing Interventional Cardiology with Label-Free Fluorescence Lifetime Imaging. Keynote lecture presented at: BioPhotonics Conference 2025; 2025 Oct 16.
- Alfonso-Garcia A. Label-free imaging of gastrointestinal disease. Presented at: 16th Annual UC Davis Research Retreat on Host-Microbe Interaction; 2025 Oct 10; Granlibakken, CA.
- Alfonso-Garcia A. Intraluminal FLIm assessment of gastrointestinal inflammation. Presented at: SCIX 2025; 2025 Oct 7; Covington, KY.
- Marcu L. Data-Centric Approach to FLIM for Intraoperative Head and Neck Cancer Margin Detection. Invited talk presented at: SCIX 2025; 2025 Oct 5–10; Covington, KY.
- Marcu L. Label-Free FLIM in Surgical Oncology. Keynote lecture presented at: World Molecular Imaging Congress; 2025 Sep 29–Oct 3; Anchorage, AK.
- Marcu L. Next-Generation Cardiovascular Imaging: The Role of FLIM and OCT. Invited talk presented at: 1st Carpathian Biophotonics Meeting; 2025 Sep 8–12; Sinaia, Romania.
- Marcu L. Interventional FLIM. Invited talk presented at: Center for Biophotonic Technology and Artificial Intelligence, University at Albany, SUNY; 2025 Jul 31.
- Islam S. AI-Driven Nanophotonic Imaging on a CMOS Platform: Precision, Speed, and Miniaturization. Invited talk presented at: IEEE International Conference on Optical MEMS and Nanophotonics; 2025 Jul 13–18; Chiang Mai, Thailand.
- Islam S. AI-Powered Nanosystems-on-a-Chip for Imaging and Sensing: Unlocking New Dimensions of Insight. Invited lecture presented at: University of Dhaka; 2025 Jul 7; Dhaka, Bangladesh.
- Marcu L. Fluorescence Lifetime Imaging in the Operating Theater. Invited seminar presented at: DTU Health Tech; 2025 Jun 17; Denmark.
- Marcu L. Biophotonics Summer School 2025. Lecturer, 4 lectures. Presented at: 12th International Graduate Summer School; 2025 Jun 7–14; Island of Ven, Sweden.
- Alfonso-Garcia A. Fluorescence lifetime imaging for disease detection and surgical guidance. Presented at: CLEO 2025; 2025 May 5; Long Beach, CA.
- Marcu L. FLIM in Neurosurgery. Invited talk presented at: OPTICA Biophotonics Congress; 2025 Apr 21–24; Coronado, CA.
- Marcu L. National Center for Interventional Biophotonic Technologies: An Overview. Invited talk presented at: Center for Label-Free Imaging and Multiscale Biophotonics Annual Symposium; 2025 Apr; University of Illinois Urbana-Champaign.
- Li XD. Low-coherence Biophotonics Imaging for the Brain. Invited seminar presented at: UC Irvine Beckman Laser Institute & Medical Clinic; 2025 Mar 27; Irvine, CA.
- Li XD. Two-photon fiberscopy for neuronal imaging in freely moving rodents. Invited talk presented at: SPIE Photonics West, Neural Imaging and Sensing Conference; 2025 Jan 27; San Francisco, CA. Conference 13303.
- Li XD. Low-coherence Biophotonics Imaging for the Brain. Invited seminar presented at: Geisel School of Medicine at Dartmouth and Thayer School of Engineering; 2025 Jan 9; Hanover, NH.
- Marcu L. Pulse-sampling FLIM in medical applications. Keynote lecture presented at: BIOS 2025, SPIE Photonics; 2025 Jan; San Francisco, CA.
- Marcu L. FLIM-guided surgical interventions. Invited talk presented at: BIOS 2025, SPIE Photonics; 2025 Jan; San Francisco, CA.
- Marcu L. Fluorescence Lifetime Imaging in Clinical Interventions. Invited seminar presented at: University of California Los Angeles; 2023 Dec.
- Li XD. Low-coherence Biophotonics for the Brain. Invited seminar presented at: Institute of NanoEngineering and MicroSystems, National Tsing Hua University; 2023 Dec; Taiwan.
- Li XD. Low-coherence Biophotonics for the Brain. Invited seminar presented at: Department of Biomedical Engineering and Center for Translational Research, National Cheng Kung University; 2023 Dec; Taiwan.
- Harsh GA. Interventional fluorescence lifetime imaging for guiding resection of malignant gliomas. Invited talk presented at: 18th World Congress of Neurosurgery; 2023 Dec; Cape Town, South Africa.
- Marcu L. Interventional FLIM: past, present, and future. Invited talk presented at: SPIE Advanced Biophotonics Conference; 2023 Nov; Jeju, Korea.
- Islam MS. AI-enabled detector array for deeper vision and sensing beyond the limit. Invited talk presented at: SciX 2023; 2023 Oct; Sparks, NV.
- Marcu L. Label-free fluorescence lifetime techniques for image-guided interventions. Invited talk presented at: Advances in Optics for Biotechnology, Medicine and Surgery XVII; 2023 Oct; Tomar, Portugal.
- Marcu L. FLIM in Surgical Oncology. Invited talk presented at: SciX 2023; 2023 Oct; Sparks, NV.
- Marcu L. Fluorescence Lifetime Imaging in Surgical Oncology. Invited talk presented at: 29th Annual Cancer Research Symposium, UC Davis; 2023 Oct.
- Marcu L. Fluorescence Lifetime Imaging of Coronary Atherosclerosis. Invited talk presented at: CVRI Retreat and Heart Day, UC Davis; 2023 Oct.
- Li XD. Low-coherence Biophotonics for the Brain. Keynote speech presented at: Light Conference 2023; 2023 Aug; Changchun, China.
- Li XD. Probing the Brain Using Low-coherence Light: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Invited talk presented at: International Nano-Optoelectronics Workshop; 2023 Jul; Wuerzburg, Germany.
- Marcu L. FLIM related. Four invited lectures presented at: BIOPHOTONICS SUMMER SCHOOL 2023, 11th International Graduate Summer School; 2023 Jun; Island of Ven.
- Li XD. Shedding Low Coherence Light on the Brain: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Keynote speech presented at: BMES Mid-Atlantic Research Day; 2023 May; Baltimore, MD.
- Li XD. Shedding Low Coherence Light on the Brain: from intra-operative guidance in patients to neural imaging in freely-moving rodents. Keynote speech presented at: CYTO 2023, International Society for Advancement of Cytometry; 2023 May; Montréal, Québec, Canada.
- Marcu L. Fluorescence lifetime and morphological imaging of coronary atherosclerosis. Invited lecture presented at: Image Guidance in PCI; 2023 Apr; Rotterdam, Netherlands.
- Li XD. 2P Fiberscopy Imaging of Neural Activities in Freely-Behaving Rodents and Beyond. Presented at: Optica Biophotonics Congress, Optics in the Life Sciences; 2023 Apr; Vancouver, BC, Canada.
- Marcu L. Label-free fluorescence lifetime imaging for intraoperative real-time guidance of neurological procedures. Invited talk presented at: 20th Annual Congress of the Society for Brain Imaging; 2023 Feb; Los Angeles, CA.
- Li XD. Mesoscopic and Microscopic Biophotonics Imaging of the Brain. Webinar presented at: Optica; 2023 Feb.
- Li XD. 2P Fiberscopy for Brain Imaging in Freely-behaving Rodents. Keynote speech presented at: SPIE Photonics West 2023; 2023 Jan.
- Marcu L. Label-Free Fluorescence Lifetime Imaging: Applications in Surgical Oncology, Precision Surgery, Intraoperative Molecular Imaging. Invited talk presented at: UPenn Abramson Cancer Center; 2022 Nov 11.
- Marcu L. Fluorescence Lifetime Imaging in Surgical Oncology. Invited seminar presented at: Miami Global Tumor Symposium; 2022 Nov 2.
- Marcu L. FLIM in Surgical Oncology. Keynote talk presented at: Virtual BioPhotonics Conference; 2022 Oct 26.
- Marcu L. Bringing Malignancy to Light in the Operating Theater. Invited talk presented at: Gordon Research Conference on Optics and Photonics in Medicine and Biology; 2022 Jul; Bates College, Lewiston, ME.
- Marcu L. FLIM-Guided Robotic Surgery. Keynote talk presented at: Hamlyn Symposium in Medical Robotics; 2022 Jun; London, UK.
- Marcu L. Bringing Malignancy to Light in the Operating Theater. Plenary talk presented at: OPTICA Congress in Biophotonics; 2022 Apr 20–23; Florida.
- Marcu L. Fluorescence Lifetime Imaging in Medical Applications. Invited seminar presented at: University of Michigan-Dearborn; 2022 Apr 1.
- Srinivasan VJ. Computational imaging and monitoring with interferometric diffuse optics. Invited talk presented at: SPIE Photonics West, Computational Optics; 2024 Jan; San Francisco, CA.
- Srinivasan VJ. Unifying diffuse optics with interferometry. Invited talk presented at: Optica Biophotonics Congress, Diffuse Optics; 2024 Apr; Fort Lauderdale, FL.
- Srinivasan VJ. Multi-scale photonics for the central nervous system in health and disease. Invited talk presented at: UC Davis BME Seminar Series; 2023 Feb.
- Srinivasan VJ. Scalable Human Brain Imaging with Time-of-Flight Filtered Diffuse Optical Interferometry. Invited talk presented at: Georgia Tech Neuro Seminar Series; 2023 Mar; Atlanta, GA.
- Srinivasan VJ. Scalable Human Brain Imaging with Time-of-Flight Filtered Diffuse Optical Interferometry. Invited talk presented at: Optica Conference on Lasers and Electro-Optics; 2023 May; San Jose, CA.
- Srinivasan VJ. Coherence engineering of a human brain interferometer to quantitatively and specifically measure cerebral blood flow. Invited talk presented at: Optica Imaging Congress, Computational Optical Sensing and Imaging; 2023 Aug; Boston, MA.
- Srinivasan VJ. Diffuse optics meets photonics. Invited tutorial presented at: 2023 IEEE Photonics Conference; 2023 Nov; Orlando, FL.
- Srinivasan VJ. Interferometric diffuse optics: past, present, and future. Invited talk presented at: SPIE Advanced Biophotonics Conference; 2023 Nov; Jeju, Korea.
- Srinivasan VJ. Invited talk presented at: IEEE Indian Institute of Science Sensors and Nanotechnology Joint Council Chapter in association with IEEE IISc Student Branch; 2022 May.
- Ma KL. Advancing AI Scaling towards the Open World: Efficiency, Responsibility, and Adaptability. Presented at: Computer Science Colloquium, University of Arizona; 2025 Nov 15; Tucson, AZ.
- Qi J. Do not throw away imaging physics in the age of AI. Edward J Hoffman Award presentation at: IEEE Medical Imaging Conference; 2025 Nov 6.
- Ma KL. AI-Assisted and Human-Centered Approaches to Visualization Design. Keynote presented at: Visual Computer Trend 2025; 2025 Jan 30; Tech Gate Vienna, Austria.
- Ma KL. Reliable AI with Human-in-the-loop Enhancement. Keynote presented at: TAICHI Workshop on AIxHCI; 2024 Dec 21; Taipei, Taiwan.
- Ozcan A. Virtual staining of label-free tissue using deep learning. Keynote talk presented at: MicroTAS 2024, 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2024 Oct 14; Montreal, Canada.
- Ozcan A. Virtual staining of label-free tissue. Keynote talk presented at: BioImaging North America Community Congress; 2024 Sep 24; University of Wisconsin-Madison, Madison, WI.
- Ozcan A. Virtual staining of label-free tissue. Invited talk presented at: Optica Frontiers in Optics Conference; 2024 Sep 23; Denver, CO.
- Strohmer T. Towards Fairness in Machine Learning via Optimal Transport. Presented at: Foundations of Data Science and Machine Learning; 2024 Sep; UC Davis, Davis, CA.
- Strohmer T. Towards Fairness in Machine Learning via Optimal Transport. Presented at: NSF CompMath PI Meeting; 2024 Jul; University of Washington, Seattle, WA.
- Qi J. From SPLIT to SIMPLE: high-resolution statistical image reconstruction methods for positronium lifetime imaging. Presented at: 5th Jagiellonian Symposium on Advances in Particle Physics and Medicine; 2024 Jun 29–Jul 7; Krakow, Poland.
- Qi J. Exploring the fascinating time axis in PET. Edward Hoffman Memorial Lecture presented at: SNMMI Annual Meeting; 2024 Jun.
- Strohmer T. The Mathematics of Privacy and Synthetic Data. Colloquium presented at: Department of Mathematics, University of California, Santa Barbara; 2024 May; Santa Barbara, CA.
- Strohmer T. Privacy and the Digital Revolution: Toward Digital Twins in Health. Presented at: Digital Health and AI Symposium, UC Davis Health; 2024 Apr; Sacramento, CA.
- Strohmer T. Data Privacy, Synthetic Data, and Computer Vision. Tutorial presented at: WACV Tutorial on AI Governance and Data Protection for Computer Vision and Beyond; 2024 Jan; Hawaii.
- Qi J. Total-body Dynamic PET Imaging and Beyond. Presented at: Department of Radiology, Weill Cornell Medicine, Cornell University; 2023 Apr 27; New York, NY.
- Qi J. Direct Estimation of Kinetic Parameters in PET. Presented at: Open Kinetic Modeling Initiative Webinar; 2023 Feb 27.
- Qi J. Total-Body PET Imaging. Presented at: Department of Nuclear Medicine, Bern University Hospital, University of Bern; 2022 Nov 14; Bern, Switzerland.