Seeing Light in 'Impossible' Places New two-photon microscopy system provides more than sixtyfold signal increase over conventional techniques
Researchers at the University of California, Davis, have developed a fast and cost-effective two-photon microscopy system capable of imaging depths previously impossible to reach in scattering tissues, such as bone and the brain.
Led by Assistant Professor of Biomedical Engineering Yi Xue, the system shows immense promise to enable scientific insights into biological features once only observable after surgical removal, like the anatomy of neurons deep in the brain. This is because the system boosts the signal strength of deep tissue microscopy systems by over 60 times while being faster and cheaper to produce than similar microscopy systems.