Archived Events

Glioblastoma (GBM) is the most aggressive form of malignant brain tumor and current treatment involves maximum surgical resection. However, accurately identifying tumor margins during surgery remains a major challenge.

Transverse chromatic aberration (TCA) was studied in human retinal visible light Optical Coherence Tomography (OCT). We devised a dispersion model-based iterative algorithm that both estimates and corrects TCA, as well as a model-free direct TCA estimation method.

Blood flow index (BFI) has proven to be a quantitative and specific signal to assess the human brain with near-infrared light.

Advanced imaging technologies are undergoing a transformation through the integration of artificial intelligence and nanophotonics.

We report the first application of high-resolution laser scanning multispectral fluorescence lifetime imaging (LS-FLIm) to characterize in detail the autofluorescence properties of human coronary arteries and plaques. Frozen coronary segments were sectioned with a microtome, and imaged.

We report the analysis conducted on 25 human coronary plaques, imaged using an integrated multispectral FLIm/polarization-sensitive OCT system, to study the optical features of high-risk oxidized lipids in atherosclerosis lesions. Imaging data were pixel-to-pixel registered with histology images.

This presentation reports our recent progress on two-photon (2P) fiberscope technology and its potential applications.

This work introduces a Quantum True Random Number Generator (QTRNG) using photon-trapping Avalanche Photodiodes (APDs) to produce high-entropy random numbers from quantum uncertainty.

Glioblastoma’s poor prognosis and treatment resistance are linked to high immune cell burden, however; current tumor microenvironment sensing in situ is limited to histopathology assessments.

This study presents a novel spatial augmentation system that integrates real-time fluorescence lifetime imaging (FLIm) with preoperative MRI navigation to enhance intraoperative guidance during brain tumor resection.

Miniaturized, mask-based integrated fluorescence microscopes offer a promising platform for endoscopic and implantable bio-imaging, enabling large field-of-view and single-shot 3D imaging.

Ultracompact ultra-lightweight two-photon (2P) fiberscopes enable real-time functional neuroimaging in freely-behaving rodents, allowing investigation of how head-mounted weight and rotational resistance affect neuronal activity.

We present a chemiluminescence vertical flow assay (CL-VFA) that achieves high-sensitivity detection of cardiac troponin I (cTnI), a gold standard biomarker for diagnosing myocardial infarction.